High resolution fiber optic surface plasmon resonance sensors with single-sided gold coatings

Feng, Dingyi; Zhou, Wenjun; Qiao, Xueguang; Albert, Jacques

doi:10.1364/oe.24.016456

Cited by 56 publications

(22 citation statements)

References 31 publications

(58 reference statements)

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“…TFBGs bring practical assets such as easy light injection, temperature fluctuations immunity and remote operation in very small volumes of analytes. To this aim, different metal configurations have been used so far [18,[27][28][29], without considerations about their relative performances in terms of biosensing.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of gold layer configuration for plasmonic fiber grating biosensors

Caucheteur¹,

Loyez²,

González-Vila³

et al. 2018

Opt. Express

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Gold-coated fiber Bragg gratings (FBGs) are nowadays a mature technology for lab-on-fiber sensing based on surface plasmon resonance (SPR) excitation. Tilted FBGs bring valuable assets such as easy light injection, remote operation in very small volumes of analytes and immunity to temperature fluctuations. Different gold configurations have been reported to date, without considering their relative performances in terms of biochemical sensing. In this work, we experimentally study the impact of the gold coating on the cladding mode distribution in the tilted FBG amplitude spectrum and subsequently on its sensitivity to cytokeratins used as biomarkers for cancer diagnosis. Some relevant configurations of gold coatings are produced and tested, relying on both the sputtering and electroless plating (ELP) processes. The obtained results confirm that the coating thickness and its roughness drive the biosensing performances. The experimental limit of detection for cytokeratins 17 sensing reaches 14 fM for the most sensitive configurations.

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Section: Introductionmentioning

confidence: 99%

Evaluation of gold layer configuration for plasmonic fiber grating biosensors

Caucheteur¹,

Loyez²,

González-Vila³

et al. 2018

Opt. Express

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“…The shape of deposited metal particles and the coating homogeneity directly impact the sensitivity and the reproducibility of plasmonic sensors. Metal deposits can be successfully applied to optical fibers using well-established technologies, such as nanoparticles immobilization [ 68 ], nanostructures elaboration [ 69 ], electroless deposition [ 70 ], evaporation or sputtering [ 71 ]. The latter is the most spread technique for planar covering, because it provides very high quality depositions.…”

Section: Interactions With Metals and Surface Biochemical Functionmentioning

confidence: 99%

Plasmonic Optical Fiber-Grating Immunosensing: A Review

Guo

González-Vila

Loyez

et al. 2017

Sensors

109

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Plasmonic immunosensors are usually made of a noble metal (in the form of a film or nanoparticles) on which bioreceptors are grafted to sense analytes based on the antibody/antigen or other affinity mechanism. Optical fiber configurations are a miniaturized counterpart to the bulky Kretschmann prism and allow easy light injection and remote operation. To excite a surface plasmon (SP), the core-guided light is locally outcoupled. Unclad optical fibers were the first configurations reported to this end. Among the different architectures able to bring light in contact with the surrounding medium, a great quantity of research is today being conducted on metal-coated fiber gratings photo-imprinted in the fiber core, as they provide modal features that enable SP generation at any wavelength, especially in the telecommunication window. They are perfectly suited for use with cost-effective high-resolution interrogators, allowing both a high sensitivity and a low limit of detection to be reached in immunosensing. This paper will review recent progress made in this field with different kinds of gratings: uniform, tilted and eccentric short-period gratings as well as long-period fiber gratings. Practical cases will be reported, showing that such sensors can be used in very small volumes of analytes and even possibly applied to in vivo diagnosis.

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“…For this, a number of methods can be used, such as thermal taping, polishing or chemical etching of the fiber [10]. However, methods based on the use of tilted fiber Bragg gratings (TFBG) are particularly interesting [24,25,26,27,28,29,30,31,32,33,34,35,36,37,38,39,40,41,42,43,44,45]. A schematic illustration of such a structure is shown in Figure 1.…”

Section: Introductionmentioning

confidence: 99%

“…There are methods for determining changes in the concentration of the measured substance by measuring the intensity of individual spectral peaks near the resonance wavelength. Thus, in [22,28,29,30,31,32,33,46], analyzing the intensity or spectral position of one or two peaks located near the spectral “constriction” was proposed. Indeed, in the case of observing small changes in the refractive index of the environment, such methods can give a relatively high resolution and detection limit.…”

Section: Introductionmentioning

confidence: 99%

Method for Determining the Plasmon Resonance Wavelength in Fiber Sensors Based on Tilted Fiber Bragg Gratings

Manuylovich

Tomyshev

Butov

2019

Sensors

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Surface plasmon resonance-based fiber-optic sensors are of increasing interest in modern sensory research, especially for chemical and biomedical applications. Special attention deserves to be given to sensors based on tilted fiber Bragg gratings, due to their unique spectral properties and potentially high sensitivity and resolution. However, the principal task is to determine the plasmon resonance wavelength based on the spectral characteristics of the sensor and, most importantly, to measure changes in environmental parameters with high resolution, while the existing indirect methods are only useable in a narrow spectral range. In this paper, we present a new approach to solving this problem, based on the original method of determining the plasmon resonance spectral position in the automatic mode by precisely calculating the constriction location on the transmission spectrum of the sensor. We also present an experimental comparison of various data processing methods in both a narrow and a wide range of the refractive indexes. Application of our method resulted in achieving a resolution of up to 3 × 10−6 in terms of the refractive index.

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High resolution fiber optic surface plasmon resonance sensors with single-sided gold coatings

Cited by 56 publications

References 31 publications

Evaluation of gold layer configuration for plasmonic fiber grating biosensors

Evaluation of gold layer configuration for plasmonic fiber grating biosensors

Plasmonic Optical Fiber-Grating Immunosensing: A Review

Method for Determining the Plasmon Resonance Wavelength in Fiber Sensors Based on Tilted Fiber Bragg Gratings

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