High resolution ECG-aided early prognostic model for comatose survivors of out of hospital cardiac arrest

Rauber, Martin; Štajer, Dušan; Noč, Marko; Schlegel, Todd T.; Starc, Vito

doi:10.1016/j.jelectrocard.2015.04.003

Cited by 5 publications

(2 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In another recent study of the ECG changes of out-of-hospital cardiac arrest during and after mild therapeutic hypothermia (Rauber et al 2013), similar results as ours were reported. The RR-interval is almost doubled during hypothermia (1019 ± 332 ms) compared to normal ECG (660 ± 161 ms).…”

Section: Discussionsupporting

confidence: 90%

In vitroarrhythmia generation by mild hypothermia: a pitchfork bifurcation type process

Xu¹,

Jacquir²,

Laurent³

et al. 2015

Physiol. Meas.

View full text Add to dashboard Cite

The neurological damage after cardiac arrest (CA) constitutes a big challenge of hospital discharge.The therapeutic hypothermia (34 • C − 32 • C) has shown its benefit to reduce cerebral oxygen demand and improve neurological outcomes after the cardiac arrest. However, it can have many adverse effects, The process of therapeutic hypothermia after cardiac arrest can be represented by a Pitchfork bifurcation type process, which could explain the different ratio of arrhythmia among the adverse effects after this therapy. This nonlinear dynamics suggests that a variable speed of cooling / rewarming, especially when passing 35 • C, would help to decrease the ratio of post-hypothermia arrhythmia and then improve the hospital output.

show abstract

Section: Discussionsupporting

confidence: 90%

In vitroarrhythmia generation by mild hypothermia: a pitchfork bifurcation type process

Xu¹,

Jacquir²,

Laurent³

et al. 2015

Physiol. Meas.

View full text Add to dashboard Cite

show abstract

“… 13 Some authors have also focused on ECG variables both during mild induced hypothermia and after rewarming, finding that some ECG variables, including QRS upslope and QRS voltages, give a good estimation of the rate of survival. 21 However, these variables are far from being easy to assess in a prehospital setting and are often not available from routine ECGs, making their prognostic utility limited to hospitalization and more specialized clinical settings. The dispersion of QT at 24 hour after hospital admission has been proven to discriminate survival with good neurological outcome.…”

Section: Discussionmentioning

confidence: 99%

Association Between Postresuscitation 12‐Lead ECG Features and Early Mortality After Out‐of‐Hospital Cardiac Arrest: A Post Hoc Subanalysis of the PEACE Study

Gentile

Baldi

Klersy

et al. 2023

JAHA

View full text Add to dashboard Cite

Background Once the return of spontaneous circulation after out‐of‐hospital cardiac arrest is achieved, a 12‐lead ECG is strongly recommended to identify candidates for urgent coronary angiography. ECG has no apparent role in mortality risk stratification. We aimed to assess whether ECG features could be associated with 30‐day survival in patients with out‐of‐hospital cardiac arrest. Methods and Results All the post‐return of spontaneous circulation ECGs from January 2015 to December 2018 in 3 European centers (Pavia, Lugano, and Vienna) were collected. Prehospital data were collected according to the Utstein style. A total of 370 ECGs were collected: 287 men (77.6%) with a median age of 62 years (interquartile range, 53–70 years). After correction for the return of spontaneous circulation‐to‐ECG time, age >62 years (hazard ratio [HR], 1.78 [95% CI, 1.21–2.61]; P =0.003), female sex (HR, 1.5 [95% CI, 1.05–2.13]; P =0.025), QRS wider than 120 ms (HR, 1.64 [95% CI, 1.43–1.87]; P <0.001), the presence of a Brugada pattern (HR, 1.49 [95% CI, 1.39–1.59]; P <0.001), and the presence of ST‐segment elevation in >1 segment (HR, 1.75 [95% CI, 1.59–1.93]; P <0.001) were independently associated with 30‐day mortality. A score ranging from 0 to 26 was created, and by dividing the population into 3 tertiles, 3 classes of risk were found with significantly different survival rate at 30 days (score 0–4, 73%; score 5–7, 66%; score 8–26, 45%). Conclusions The post‐return of spontaneous circulation ECG can identify patients who are at high risk of mortality after out‐of‐hospital cardiac arrest earlier than other forms of prognostication. This provides important risk stratification possibilities in postcardiac arrest care that could help to direct treatments and improve outcomes in patients with out‐of‐hospital cardiac arrest.

show abstract

Therapeutic Hypothermia in Post-Cardiac Arrest and Myocardial Infarction

Polderman

Noč

Kurz

et al. 2015

Therapeutic Hypothermia and Temperature Management

View full text Add to dashboard Cite

High resolution ECG-aided early prognostic model for comatose survivors of out of hospital cardiac arrest

Cited by 5 publications

References 27 publications

In vitroarrhythmia generation by mild hypothermia: a pitchfork bifurcation type process

In vitroarrhythmia generation by mild hypothermia: a pitchfork bifurcation type process

Association Between Postresuscitation 12‐Lead ECG Features and Early Mortality After Out‐of‐Hospital Cardiac Arrest: A Post Hoc Subanalysis of the PEACE Study

Therapeutic Hypothermia in Post-Cardiac Arrest and Myocardial Infarction

Contact Info

Product

Resources

About