High Prevalence of Seborrhoeic Dermatitis on the Face and Scalp in Mountain Guides

Moehrle, Matthias; Dennenmoser, Bernhard; Schlagenhauff, Bettina; Thomma, Sybille; Garbe, Claus

doi:10.1159/000018458

Cited by 46 publications

(29 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Of course, variances between individuals also may result from patterns of conduct, inasmuch as persons exposed to one risk factor (smoking) are often exposed to others as well, such as intake of androgens or their precursor (such as dehydroepiandrosterone), or of progestins with androgenic activity (in oral contraceptives and hormonal replacement therapy), excessive ultraviolet light exposure and stress, all of which have been implicated in one way or another in the pathogenesis of alopecia and associated conditions of the scalp [35, 36, 37, 38, 39]. …”

Section: Introductionmentioning

confidence: 99%

Association between Smoking and Hair Loss: Another Opportunity for Health Education against Smoking?

Trüeb¹

2003

Dermatology

103

View full text Add to dashboard Cite

Besides being the single most preventable cause of significant morbidity and an important cause of death in the general population, tobacco smoking has been associated with adverse effects on the skin. Smoke-induced premature skin ageing has attracted the attention of the medical community, while only recently an observational study has indicated a significant relationship between smoking and baldness. The mechanisms by which smoking causes hair loss are multifactorial and are probably related to effects of cigarette smoke on the microvasculature of the dermal hair papilla, smoke genotoxicants causing damage to DNA of the hair follicle, smoke-induced imbalance in the follicular protease/antiprotease systems controlling tissue remodeling during the hair growth cycle, pro-oxidant effects of smoking leading to the release of pro-inflammatory cytokines resulting in follicular micro-inflammation and fibrosis and finally increased hydroxylation of oestradiol as well as inhibition of the enzyme aromatase creating a relative hypo-oestrogenic state. In view of the psychological impact of androgenetic alopecia on affected men and women, increasing public awareness of the association between smoking and hair loss offers an opportunity for health education against smoking that may be more effective than the link between smoking and facial wrinkles or grey hair, since the latter can be effectively counteracted by current aesthetic dermatologic procedures, while treatment options for androgenetic alopecia are limited.

show abstract

Section: Introductionmentioning

confidence: 99%

Association between Smoking and Hair Loss: Another Opportunity for Health Education against Smoking?

Trüeb¹

2003

Dermatology

103

View full text Add to dashboard Cite

show abstract

“…The main differences between normal looking skin and seborrheic dermatitis are the yeast density and the elicited inflammatory response [1][2][3][4]. Some other interfering factors, such as cold weather and stressful periods, may also aggravate the skin condition [5].…”

mentioning

confidence: 99%

Seborrheic Dermatitis Today, Gone Tomorrow? The Link between the Biocene and Treatment

Pierard

2003

Dermatology

View full text Add to dashboard Cite

“…By contrast, mountain guides have been reported to be particularly affected by these disorders [20]. These observations may be put in perspective with the natural antimicrobial defense mechanisms.…”

Section: Dandruff Seborrheic Dermatitis and The Environmentmentioning

confidence: 99%

The Key Role of Corneocytes in Pityrosporoses

Pierard¹,

Xhauflaire-Uhoda²,

Piérard-Franchimont³

2006

Dermatology

View full text Add to dashboard Cite

Pityrosporoses encompass various Malassezia-driven conditions. Dandruff and seborrheic dermatitis are members of this family of disorders. Their precise pathomechanisms have not been completely elucidated so far. This review focuses on the role of corneocytes in these disorders. Malassezia yeasts are not evenly distributed at the surface of the stratum corneum. Rather, they are clumped on some corneocytes while other corneocytes in their vicinity are almost free of these microorganisms. The corneocytes heavily coated by yeasts suggest a cell-related defect in the mechanisms controlling the skin biocene including the natural antimicrobial peptides and nitric oxide. Most environmental factors influencing pityrosporoses indeed affect the natural human defenses against certain microorganisms. We frame as a hypothesis that the primary defect in some Malassezia-driven disorders resides in the corneocytes and their precursor keratinocytes.

show abstract

High Prevalence of Seborrhoeic Dermatitis on the Face and Scalp in Mountain Guides

Cited by 46 publications

References 8 publications

Association between Smoking and Hair Loss: Another Opportunity for Health Education against Smoking?

Association between Smoking and Hair Loss: Another Opportunity for Health Education against Smoking?

Seborrheic Dermatitis Today, Gone Tomorrow? The Link between the Biocene and Treatment

The Key Role of Corneocytes in Pityrosporoses

Contact Info

Product

Resources

About