High-performance liquid chromatography/electrospray ionization-mass spectrometry for simultaneous determination of taurine and 10 water-soluble vitamins in multivitamin tablets

Chen, Zhi; Chen, Bo; Yao, Shouzhuo

doi:10.1016/j.aca.2006.03.099

Cited by 137 publications

(84 citation statements)

References 29 publications

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“…So it becomes necessary to develop a simple, sensitive and reliable method to analyze nicotinamide in pharmaceutical preparations. Determination of nicotinamide has been already extensively studied by different methods like luminescence, 3 surfaceenhanced Raman detection, 4 reversed-phase liquid chromatography, 5 micellar liquid chromatography, 6 and highperformance liquid chromatography; 7 however, electrochemical methods are more sensitive and simple to analyze in a complex matrix, due to nicotinamide's more negative reduction potential as compared to that of other vitamins. Also, biologically important molecules like NAD and NADH on decomposition give small amounts of nicotinamide; hence, knowledge of the electrochemical properties of nicotinamide and its reduced forms are helpful in characterization of the nucleotides.…”

Section: Introductionmentioning

confidence: 99%

Polarographic Behavior of Nicotinamide in Surfactant Media and Its Determination in Cetyltrimethylammonium Bromide Surfactant System

Kotkar

Srivastava

2008

ANAL. SCI.

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Section: Introductionmentioning

confidence: 99%

Polarographic Behavior of Nicotinamide in Surfactant Media and Its Determination in Cetyltrimethylammonium Bromide Surfactant System

Kotkar

Srivastava

2008

ANAL. SCI.

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“…(Ghasemi and Abbasi, 2005;Chen et al, 2006;Ciulu et al, 2011). Depending on the nature and form of the food material, a mere dissolution might not be applicable when the test sample cannot be dissolved in its raw form (e.g.…”

Section: Preparation Of Test Sample For Hplcmentioning

confidence: 99%

Simultaneous detection of water-soluble vitamins using the High Performance Liquid Chromatography (HPLC) - a review

Abano

Dadzie

2014

Croat. J. Food Sci. Technol.

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SummaryThe water-soluble vitamins (WSV): ascorbic acid (vitamin C), thiamine (B1), riboflavin (B2), niacin (B3), panthothenic acid (B5), pyridoxine, and pyridoxal (B6), folic acid (B9), biotin(B8) , and B12 are very essential in the diet of humankind. As a result of ever increasing pressures from both consumers and legal enforcers, to specify accurately nutritive compositions of WSV that are present in food materials, many researchers have attempted to fill this niche through the provision of highly sensitive and rapid high performance liquid chromatography (HPLC) procedures. In view of the health benefits of WSV, a replete of HPLC methods have been developed for simultaneous determination of their contents in nature and fortified food samples, nutritional supplements, as well as blood plasmas. The rate of losses of these vitamins during food processing and analysis, in addition to their transient dynamics, presents complexities in developing a highly sensitive HPLC procedure for their simultaneous separations and assays. This review critically assesses the different HPLC procedures developed by researchers and available in the open literature for simultaneous determination of water-soluble vitamins (WSV) in dried tropical fruits materials. The study revealed that not a single chromatographic run developed by researchers can simultaneously elute all the WSV at a time. However, the HPLC procedures that are capable of determining all the WSV were coupled with electrospray ionization mass spectroscopy (ESI-MS), thus making the set-up expensive.

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“…Several analytical methods for determination MET such as electrochemical and electrophoretic, 5 reflectometric, 6 spectrophotometry, 7 HPLC 8 and liquid chromatography-mass spectrometry (LC/MS) for bioequivalence study. 9 Furthermore, several analytical methods for quantification B1 and B6 such as densitometry and spectrofotometry in combination with multivariate calibration, 10 capilary zone electrophoresis, 11 HPLC, 12,13 and LC/MS 14,15 have beed used. The combination of MET, B1 and B6 is comercially available in tablet dosage form, and the widely used analytical method is HPLC.…”

Section: Introductionmentioning

confidence: 99%

Simultaneous Determination of Metamizole, Thiamin and Pyridoxin Using UV-Spectroscopy in Combination with Multivariate Calibration

Chotimah¹,

Sudjadi²,

Riyanto³

et al. 2015

Adv Pharm Bull

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High-performance liquid chromatography/electrospray ionization-mass spectrometry for simultaneous determination of taurine and 10 water-soluble vitamins in multivitamin tablets

Cited by 137 publications

References 29 publications

Polarographic Behavior of Nicotinamide in Surfactant Media and Its Determination in Cetyltrimethylammonium Bromide Surfactant System

Polarographic Behavior of Nicotinamide in Surfactant Media and Its Determination in Cetyltrimethylammonium Bromide Surfactant System

Simultaneous detection of water-soluble vitamins using the High Performance Liquid Chromatography (HPLC) - a review

Simultaneous Determination of Metamizole, Thiamin and Pyridoxin Using UV-Spectroscopy in Combination with Multivariate Calibration

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