High‐frequency ultrasound as a scientific tool for skin imaging analysis

Vergilio, Mariane Massufero; Silva, Silas Arandas Monteiro e; Jales, Rodrigo Menezes; Leonardi, Gislaine Ricci

doi:10.1111/exd.14363

Cited by 19 publications

(31 citation statements)

References 109 publications

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“…The analyses were performed by applying the transducer to the test area on previously demarcated regions of the skin. Ultrasonographic gel (RMC ® ) was used at the interface between the transducer and the skin to obtain a better‐quality images 18 …”

Section: Methodsmentioning

confidence: 99%

“…On the contrary, effectiveness studies have been increasingly improved. Currently, skin image analysis by high‐frequency ultrasound (HFUS) has received considerable attention 18 18,19 …”

Section: Introductionmentioning

confidence: 99%

“…Currently, skin image analysis by high‐frequency ultrasound (HFUS) has received considerable attention 18 18,19 …”

Section: Introductionmentioning

confidence: 99%

“…The application of HFUS is essential in complete skin evaluations since the high frequency enables the detailed, real‐time visualization of the epidermis, dermis, and subcutaneous tissue, allowing for a meticulous characterization of skin parameters 18 …”

Section: Introductionmentioning

confidence: 99%

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In vivo evaluation of topical ascorbic acid application on skin aging by 50 MHz ultrasound

Vergilio

Aiello

Furlan

et al. 2022

J of Cosmetic Dermatology

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Introduction Ascorbic acid (AA) is a powerful antioxidant capable of acting significantly both in the prevention and treatment of the skin aging process. One way to assess the in vivo efficacy of anti‐aging treatments is by using the high‐frequency ultrasound (HFUS) skin image analysis technique, a non‐invasive approach that allows for a new level of evaluating the effectiveness of dermatological and cosmetic products. The aim of the present study was to assess the performance of a topical emulsion of liquid crystalline structures containing AA using the 50 MHz HFUS skin image analysis method. Methods Twenty‐five healthy female participants between 35 and 60 years were included, all of whom randomly applied a placebo formulation and an AA‐containing formulation to each forearm, once a day, for 30 days. HFUS measurements were performed before using the products (T0), 2 h later (T2h), and after 30 days of use (T30d). The analyzed parameters included total skin, dermal, and epidermal echogenicity; variation and mean thickness of total skin, the epidermis and dermis; and surface roughness. Statistical analyses were performed using the Friedman test, followed by Dunn's test for comparisons of multiple means (α = 0.05). Results A significant increase in total skin and dermal echogenicity was observed after topical AA application. Conclusion Our findings suggest that collagen synthesis significantly increased after topical therapy with AA, which was responsible for the increment in dermal echogenicity. This study showed, through the HFUS technique, that the topical use of AA promoted dermal redensification after 30 days of application.

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Section: Methodsmentioning

confidence: 99%

“…On the contrary, effectiveness studies have been increasingly improved. Currently, skin image analysis by high‐frequency ultrasound (HFUS) has received considerable attention 18 18,19 …”

Section: Introductionmentioning

confidence: 99%

“…Currently, skin image analysis by high‐frequency ultrasound (HFUS) has received considerable attention 18 18,19 …”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

In vivo evaluation of topical ascorbic acid application on skin aging by 50 MHz ultrasound

Vergilio

Aiello

Furlan

et al. 2022

J of Cosmetic Dermatology

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“…Despite these reports, there are generally no obvious contraindications for the use of HFUS imaging, and the clinical application value is still great. There is potential and practical value to using advanced emerging HFUS imaging as a scientific tool for cosmetic medicine imaging technology ( Vergilio et al, 2021 ).…”

Section: Application In Other Areas Of Medical Cosmetologymentioning

confidence: 99%

Emerging High-Frequency Ultrasound Imaging in Medical Cosmetology

Yaping

et al. 2022

Front. Physiol.

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Cosmetic skin diseases are a part of many dermatological concerns brought up by patients, which negatively affect mental health and quality of life. Imaging technology has an established role in the diagnosis of cosmetic skin diseases by recognizing information on deep skin lesions. Due to the complex physiological and pathological nature of cosmetic skin diseases, the diagnostic imaging performance varies greatly. Developing noninvasive technology models with wide applicability, particularly high-frequency ultrasound (HFUS), which is able to achieve high-resolution imaging of the skin from the stratum corneum down to the deep fascia, is of great significance to medical cosmetology. To explore the great potential of HFUS in cosmetic skin diseases, a narrative review of literature from PubMed and Web of Science published between 1985 and 2022 was conducted. This narrative review focuses on the progression of HFUS imaging in medical cosmetology, especially on its promising application in the quantitative evaluation and differential diagnosis of cutaneous pathological scar, port wine stain (PWS), acne, skin aging, and other cosmetic applications.

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Sub-Terahertz and Terahertz Waves for Skin Diagnosis and Therapy

Koul

Kaurav

2022

Sub-Terahertz Sensing Technology for Biomedical Applications

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High‐frequency ultrasound as a scientific tool for skin imaging analysis

Cited by 19 publications

References 109 publications

In vivo evaluation of topical ascorbic acid application on skin aging by 50 MHz ultrasound

In vivo evaluation of topical ascorbic acid application on skin aging by 50 MHz ultrasound

Emerging High-Frequency Ultrasound Imaging in Medical Cosmetology

Sub-Terahertz and Terahertz Waves for Skin Diagnosis and Therapy

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