High frequency harmonic imaging in presence of intravascular stents

Frijlink, M.E.; Goertz, David E.; Foster, F. Stuart; Steen, A.F.W. van der

doi:10.1109/ultsym.2003.1293390

Cited by 3 publications

(2 citation statements)

References 7 publications

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“…A second study described the experimental characterization of fundamental and second harmonic beams of a spherically focused PVDF transducer in the 20 to 40 MHz range [16]. In a previous study, we showed the suppression of stent imaging artifacts when high-frequency THI (transmit f c = 20 MHz, receive f c = 40 MHz) was applied in vitro [17]. However, results of THI in any IVUS application with a conventional rotating IVUS catheter in phantoms or in vivo have not been reported.…”

Section: Introductionmentioning

confidence: 99%

Intravascular ultrasound tissue harmonic imaging in vivo

Frijlink

Goertz

Damme

et al. 2006

IEEE Trans. Ultrason., Ferroelect., Freq. Contr.

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Tissue harmonic imaging (THI) has been shown to increase image quality of medical ultrasound in the frequency range from 2 to 10 MHz and might, therefore, also be used to improve image quality in intravascular ultrasound (IVUS). In this study we constructed a prototype IVUS system that could operate in both fundamental frequency and second harmonic imaging modes. This system uses a conventional, continuously rotating, single-element IVUS catheter and was operated in fundamental 20 MHz, fundamental 40 MHz, and harmonic 40 MHz modes (transmit 20 MHz, receive 40 MHz). Hydrophone beam characterization measurements demonstrated the build-up of a second harmonic signal as a function of increasing pressure. Imaging experiments were conducted in both a tissuemimicking phantom and in an atherosclerotic animal model in vivo. Acquisitions of fundamental 20 and 40 MHz and second harmonic acquisitions resulted in cross sections of the phantom and a rabbit aorta. The harmonic results of the imaging experiments showed the feasibility of intravascular THI with a conventional IVUS catheter both in a phantom and in vivo. The harmonic acquisitions also showed the potential of THI to reduce image artifacts compared to fundamental imaging.

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Section: Introductionmentioning

confidence: 99%

Intravascular ultrasound tissue harmonic imaging in vivo

Frijlink

Goertz

Damme

et al. 2006

IEEE Trans. Ultrason., Ferroelect., Freq. Contr.

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“…This beneficial effect comes at the cost of lower signal levels of the harmonics, which can be overcome by careful design of the transducer for harmonic imaging [3,4]. Initial studies have suggested the feasibility of THI in IVUS imaging [5,6], but these were carried out with transducers that were not optimized for the purpose. Various harmonic imaging transducers for diagnostic medical highfrequency ultrasound are described in literature [2,[7][8][9], mostly based on PVDF and lithium niobate.…”

Section: Introductionmentioning

confidence: 99%

A 20-40 MHz ultrasound transducer for intravascular harmonic imaging

Vos

Frijlink

Droog

et al.

IEEE Ultrasonics Symposium, 2004

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Recent studies have suggested the feasibility of tissue harmonic imaging (THI) with intravascular ultrasound (IVUS). This paper describes the design, fabrication and characterization of a piezo-electric transducer optimized for tissue harmonic IVUS. Ideally, such a transducer should efficiently transmit a short acoustic pulse at the fundamental transmission frequency and should be sensitive to its second harmonic echo, for which we have chosen 20 MHz and 40 MHz, respectively. The intravascular application limits the transducer dimensions to 0.75 mm by 1 mm. The transducer comprises of a single piezoelectric layer design with additional passive layers for tuning and efficiency improvement, and the Krimholtz-Leedom-Matthaei (KLM) model was used to find iteratively optimal material properties of the different layers. Based on the optimized design a prototype of the transducer was built. The transducer was characterized by water-tank hydrophone measurements and pulse-echo measurements. These measurements showed the transducer to have two frequency bands around 20 MHz and 40 MHz with -6dB fractional bandwidths of 30 % and 25 %, and round-trip insertion losses of -19 dB and -34 dB, respectively.

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