Intravascular ultrasound tissue harmonic imaging in vivo

Frijlink, M.E.; Goertz, David E.; Damme, Luc C.A. van; Krams, R.; Steen, Antonius F.W. van der

doi:10.1109/tuffc.2006.116

Cited by 39 publications

(14 citation statements)

References 22 publications

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“…Such system would launch the probing wave at the fundamental frequency of 20 MHz and receive the echoes at 40 MHz. A prototype of an HF system operating at 2 nd harmonic has been recently tested using a conventional continuously rotating catheter [54]. Comparison of the images of the crosssections of rabbit atherosclerotic aorta obtained at 20 and 40 MHz confirmed that the higher frequency (i.e.…”

Section: Emerging High Frequency Technologiesmentioning

confidence: 81%

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High frequency biomedical and industrial ultrasound applications

Lewin¹

2007

Proceedings of the Interntional Congress on Ultrasonics

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Technical advances and selected developments in high frequency (HF) (above 20 MHz) ultrasound are reviewed along with current clinical uses that include intraluminal, ophthalmic, dermatologic and odontologic imaging. Pre-clinical applications that entail research using small animal imaging are explored and molecular imaging that involves probes or biomarkers for illuminating specific targets and aiding in diagnosis is also examined. Application of micron resolution ultrasound images in bone structure analysis is pointed out and the motivation behind visualization of the living cells using super-high frequency sources operating close to 1GHz is discussed. A few selected applications of HF ultrasound imaging in non-destructive testing, particularly in detecting flaws in adhesion layers and bonding quality are also included. Future developments of HF ultrasound energy are pointed out.

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Section: Emerging High Frequency Technologiesmentioning

confidence: 81%

“…Also, it may be useful in characterization of vulnerable plague [54]. In addition, in the recent studies performed using small animals, myocardial elastography was determined to be a promising method in noninvasive evaluation of regional myocardial function.…”

Section: Small Animal Imaging -Pre-clinical Applicationsmentioning

confidence: 99%

High frequency biomedical and industrial ultrasound applications

Lewin¹

2007

Proceedings of the Interntional Congress on Ultrasonics

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“…Due to its high resolution, tissue harmonic imaging (THI) is useful, and many studies have been done [9,10]. THI uses harmonic components generated as nonlinear distortion caused by ultrasonic propagation in living tissue for imaging.…”

Section: Introductionmentioning

confidence: 99%

Compensation of Frequency-Dependent Attenuation for Tissue Harmonic Pulse Compression Imaging

Tagawa¹,

Hiraoka²,

Akiyama³

2018

Compendium of New Techniques in Harmonic Analysis

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Tissue harmonic imaging (THI) is highly effective for correct diagnosis. On the other hand, pulse compression is often used in a radar system and an ultrasound imaging system to perform high SNR measurement. Therefore, the performance of pulse compression of tissue harmonic imaging is required to be improved. The frequency-dependent attenuation (FDA) is a crucial problem in medical tissue imaging. In the pulse compression imaging, the deterioration of echoes by the FDA lowers the performance of a matched filtering using an ideal transmitted pulse as a template signal. Since, especially in the harmonic imaging, higher-frequency components are used for imaging than the fundamental imaging, the compensation of the FDA is strongly important for high-definition imaging. In this study, we examine a method to reduce the influence of the FDA on harmonics.

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“…Significant academic innovations such as IVUS flow [11], [12], IVUS palpography [8], [13], harmonic IVUS [14], [15] and contrast-enhanced IVUS [9], [16] were to date not taken up by industry. Furthermore, IVUS remains a niche technology, whose clinical practice did not vastly expand nor disappear.…”

Section: Introductionmentioning

confidence: 99%

Mapping Intravascular Ultrasound Controversies in Interventional Cardiology Practice

Maresca

Adams

Maresca³

et al. 2014

PLoS ONE

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Intravascular ultrasound is a catheter-based imaging modality that was developed to investigate the condition of coronary arteries and assess the vulnerability of coronary atherosclerotic plaques in particular. Since its introduction in the clinic 20 years ago, use of intravascular ultrasound innovation has been relatively limited. Intravascular ultrasound remains a niche technology; its clinical practice did not vastly expand, except in Japan, where intravascular ultrasound is an appraised tool for guiding percutaneous coronary interventions. In this qualitative research study, we follow scholarship on the sociology of innovation in exploring both the current adoption practices and perspectives on the future of intravascular ultrasound. We conducted a survey of biomedical experts with experience in the technology, the practice, and the commercialization of intravascular ultrasound. The collected information enabled us to map intravascular ultrasound controversies as well as to outline the dynamics of the international network of experts that generates intravascular ultrasound innovations and uses intravascular ultrasound technologies. While the technology is praised for its capacity to measure coronary atherosclerotic plaque morphology and is steadily used in clinical research, the lack of demonstrated benefits of intravascular ultrasound guided coronary interventions emerges as the strongest factor that prevents its expansion. Furthermore, most of the controversies identified were external to intravascular ultrasound technology itself, meaning that decision making at the industrial, financial and regulatory levels are likely to determine the future of intravascular ultrasound. In light of opinions from the responding experts', a wider adoption of intravascular ultrasound as a stand-alone imaging modality seems rather uncertain, but the appeal for this technology may be renewed by improving image quality and through combination with complementary imaging modalities.

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Intravascular ultrasound tissue harmonic imaging in vivo

Cited by 39 publications

References 22 publications

High frequency biomedical and industrial ultrasound applications

High frequency biomedical and industrial ultrasound applications

Compensation of Frequency-Dependent Attenuation for Tissue Harmonic Pulse Compression Imaging

Mapping Intravascular Ultrasound Controversies in Interventional Cardiology Practice

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