High Energy Thermotherapy Versus Transurethral Resection in the Treatment of Benign Prostatic Hyperplasia: Results of a Prospective Randomized Study With 1 Year of Followup

D'ancona, F. C. H.; Francisca, E.A.E.; Witjes, Wim P.J.; Welling, Leonardo C.; Debruyne, F. M. J.; Rosette, Jean J.M.C.H. de la

doi:10.1097/00005392-199707000-00035

Cited by 71 publications

(47 citation statements)

References 26 publications

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“…The results in both groups are comparable with those reported by others [7,20,23,24]. Comparing TUMT and the control group, the standard operation was the most effective, as others report [13,17]. Some studies of high-energy TUMT have reported slightly larger increases in flow rate than in the present study but all randomized trials have consistently reported the best improvements after TURP.…”

Section: Discussionsupporting

confidence: 90%

“…The results for symptom reduction are comparable with those reported by others [4,8,10,17,22]. In a large study by Emberton et al [2] of > 3000 patients treated by TURP the AUA score decreased from a mean of 20.1 at baseline to 7.4 at 3 months.…”

Section: Discussionsupporting

confidence: 87%

“…In controlled studies comparing TUMT (with the Prostatron) and TURP only one of the available software versions has been used in all patients [13,17]. The manufacturer recommends the use of Prostasoft v2.0 in patients with small prostates and v2.5 for larger prostates.…”

Section: Introductionmentioning

confidence: 99%

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Transurethral interstitial laser coagulation of the prostate and transurethral microwave thermotherapy vs transurethral resection or incision of the prostate: results of a randomized, controlled study in patients with symptomatic benign prostatic hyperplasia

2002

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Objective To compare the efficacy and frequency of complications of transurethral interstitial laser coagulation (ILC) and transurethral microwave thermotherapy (TUMT) with transurethral resection or incision of the prostate (TURP/TUIP) in patients with symptomatic benign prostatic hyperplasia (BPH). Patients and methods Forty-eight patients were randomized to undergo ILC, 46 to TUMT and 24 to TURP/ TUIP; they were followed for 6 months and the outcome analysed on an intention-to-treat basis. Results At 6 months the symptom scores and maximum urinary flow rate (Q max ) had improved significantly in all groups. At 6 months the mean symptom score was 9.2 in both experimental groups and 6.8 in the control group ( P > 0.05); the mean Q max was 20.6 mL/s in the control group, 16.2 in the ILC group ( P > 0.05 vs control) and 13.2 in the TUMT group ( P < 0.05 vs. the control group). In the TUMT group patients developing urinary retention afterward had a significantly greater increase in Q max than those who did not. The types of complications in the three groups varied. Urinary tract infection occurred frequently in the experimental groups, especially after ILC, whereas the 'well-known' complications of TURP occurred in the control group.Overall, 36% in the ILC, 54% in the TUMT and 73% in the control group had no complications (retrograde ejaculation excluded) during the first 6 months. One patient in the TUMT group underwent TURP after 3 months, whereas no patients in the ILC or the control group were re-treated for BPH within the first 6 months. Conclusion In the short term both ILC and TUMT are reasonable alternatives to standard transurethral surgery for symptomatic BPH, where the reduction of symptoms is the primary goal of treatment. However, both ILC and TUMT were associated with morbidity, although the complication profiles differed from those after TURP/TUIP. Both ILC and TUMT seem advantageous in some patients because of the reduced risk of bleeding and the eliminated risk of TUR syndrome, and because TUMT only requires local anaesthesia. Thus, as neither treatment is better in all aspects, the advantages of one technique over the other must be weighed when deciding how to treat each patient.

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Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 87%

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Transurethral interstitial laser coagulation of the prostate and transurethral microwave thermotherapy vs transurethral resection or incision of the prostate: results of a randomized, controlled study in patients with symptomatic benign prostatic hyperplasia

2002

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“…Six RCTs, reported in 19 papers, 86,124,[165][166][167][168][169][207][208][209][210][211][212][213][214][215][216][217][218] were eligible for this comparison, in which a total of 549 participants were randomised. The number of participants randomised to TUMT or TURP ranged from 2 168 to 99.…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

Systematic review and economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic enlargement

Lourenço

Armstrong²,

N’Dow³

et al. 2008

Health Technol Assess

116

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Systematic review and economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic enlargement. Lourenco, T.; Armstrong, N.; N'Dow, J.; Nabi, G.; Deverill, M.; Pickard, R.; Vale, L.; MacLennan, G.; Fraser, C.; McClinton, S.; Wong, S.; Coutts, A.; Mowatt, G.; Grant, A. Published in: Health Technology Assessment Publication date: 2008 Document VersionPublisher's PDF, also known as Version of record Link to publication in Discovery Research Portal Citation for published version (APA):Lourenco, T., Armstrong, N., N'Dow, J., Nabi, G., Deverill, M., Pickard, R., ... Grant, A. (2008). Systematic review and economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic enlargement. Health Technology Assessment, 12(35). General rightsCopyright and moral rights for the publications made accessible in Discovery Research Portal are retained by the authors and/or other copyright owners and it is a condition of accessing publications that users recognise and abide by the legal requirements associated with these rights.• Users may download and print one copy of any publication from Discovery Research Portal for the purpose of private study or research.• You may not further distribute the material or use it for any profit-making activity or commercial gain.• You may freely distribute the URL identifying the publication in the public portal. Take down policyIf you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Download date: 12. May. 2018 Health Technology Assessment 2008; Vol. 12: No. 35 Health Technology Assessment NIHR HTA Programme www.hta.ac.uk November 2008 Systematic review and economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic enlargement How to obtain copies of this and other HTA Programme reports. An electronic version of this publication, in Adobe Acrobat format, is available for downloading free of charge for personal use from the HTA website (www.hta.ac.uk). A fully searchable CD-ROM is also available (see below).Printed copies of HTA monographs cost £20 each (post and packing free in the UK) to both public and private sector purchasers from our Despatch Agents.Non-UK purchasers will have to pay a small fee for post and packing. For European countries the cost is £2 per monograph and for the rest of the world £3 per monograph.You can order HTA monographs from our Despatch Agents:-fax (with credit card or official purchase order) -post (with credit card or official purchase order or cheque) -phone during office hours (credit card only).Additionally the HTA website allows you either to pay securely by credit card or to print out your order and then post or fax it. NHS libraries can subscribe free of charge. Public libraries can subscribe at a very reduced cost of £100 for each volume (normally comprising 30-40 titles). The commercial subscription rate is £3...

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“…Comparison of high energy TUMT (HE-TUMT) versus TURP demonstrated an average symptom score improvement of 68% at 1 year which stabilised at 57% after 2.4 years follow-up [87]. Such symptomatic improvement was comparable to TURP at both time intervals (74% and 62% respectively).…”

Section: Resultsmentioning

confidence: 99%

Invasive and Minimally Invasive Treatment Modalities for Lower Urinary Tract Symptoms: What Are the Relevant Differences in Randomised Controlled Trials?

Tubaro¹,

Vicentini²,

Renzetti³

et al. 2000

Eur Urol

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High Energy Thermotherapy Versus Transurethral Resection in the Treatment of Benign Prostatic Hyperplasia: Results of a Prospective Randomized Study With 1 Year of Followup

Abstract: Satisfactory results were obtained after both treatments, with improvements following high energy microwave thermotherapy being in the same range as those after transurethral resection of the prostate.

Cited by 71 publications

References 26 publications

Transurethral interstitial laser coagulation of the prostate and transurethral microwave thermotherapy vs transurethral resection or incision of the prostate: results of a randomized, controlled study in patients with symptomatic benign prostatic hyperplasia

Transurethral interstitial laser coagulation of the prostate and transurethral microwave thermotherapy vs transurethral resection or incision of the prostate: results of a randomized, controlled study in patients with symptomatic benign prostatic hyperplasia

Systematic review and economic modelling of effectiveness and cost utility of surgical treatments for men with benign prostatic enlargement

Invasive and Minimally Invasive Treatment Modalities for Lower Urinary Tract Symptoms: What Are the Relevant Differences in Randomised Controlled Trials?

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