High efficient probes with Schiff base functional receptors for hypochlorite sensing under physiological conditions

Huang, Yangyang; Wang, Meng-Jia; Yang, Zheng; She, Mengyao; Wang, Shu; Liu, Ping; Li, Jianli; Shi, Zujin

doi:10.1016/j.cclet.2014.05.011

Cited by 14 publications

(1 citation statement)

References 28 publications

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“…Compared with the above-mentioned methods, the fluorescent probes have advantages such as high sensitivity, high selectivity, fast response time, and a wide detection range. Moreover, the detection process generally does not damage the sample and has little harm to cells [ 9 , 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 ]. In this paper, different categories of recently discovered ClO − probes are classified based on their detection mechanisms.…”

Section: Introductionmentioning

confidence: 99%

Research Progress of Small Molecule Fluorescent Probes for Detecting Hypochlorite

Song

Yuan

et al. 2021

Sensors

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Hypochlorous acid (HOCl) generates from the reaction between hydrogen peroxide and chloride ions via myeloperoxidase (MPO)-mediated in vivo. As very important reactive oxygen species (ROS), hypochlorous acid (HOCl)/hypochlorite (OCl−) play a crucial role in a variety of physiological and pathological processes. However, excessive or misplaced production of HOCl/OCl− can cause variety of tissue damage and human diseases. Therefore, rapid, sensitive, and selective detection of OCl− is very important. In recent years, the fluorescent probe method for detecting hypochlorous acid has been developed rapidly due to its simple operation, low toxicity, high sensitivity, and high selectivity. In this review, the progress of recently discovered fluorescent probes for the detection of hypochlorous acid was summarized with the aim to provide useful information for further design of better fluorescent probes.

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Section: Introductionmentioning

confidence: 99%

Research Progress of Small Molecule Fluorescent Probes for Detecting Hypochlorite

Song

Yuan

et al. 2021

Sensors

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A Nontoxic, Bio‐friendly, Fluorescent Chemodosimeter for Hypochlorite Detection in Living Cells through the Oxidation of Hypochlorite on a Hydrazide System

et al. 2018

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A simple, nontoxic, bio‐friendly, fluorescent chemodosimeter based on 2,4‐dinitrobenzene and thio‐rhodamine was designed and synthesized for the detection of toxic hypochlorite with high selectivity and sensitivity. First time, the oxidation property of the hypochlorite ion was applied on a hydrazide system (Ar−NH−N<). Practical utility of the sensor was proved through simple and fast visual detection of hypochlorite. Absorption and emission spectra exhibited the fast sensing capability of the sensor towards hypochlorite. The nontoxic, bio‐friendly properties of the sensor in living cells increased its real time practical applicability as it was successfully applied for in‐vitro detection of toxic hypochlorite in living cells.

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Sensitive and Selective “Turn-On” Chemodosimetric Probes for Fe3+ Based on a Skeleton of 2-Hydroxy-1-Naphthaldehyde

et al. 2017

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A naked-eye colored chemodosimeteric probes 4a-f, based on Schiff-azo dye conjugates were synthesized and characterized. All compounds 4a-f exhibited excellent selectivity and high sensitivity in absorbance toward detection of Fe in alcoholic solutions under neutral pH conditions. The detection limit of the probe was shown to be up to 0.05 ppm. A simple paper test strip system for the rapid monitoring of Fe was developed, indicating their convenient use in environmental samples. Electrochemical analysis of metal free conjugates and iron chelated probes confirmed the chelation of ligands. Graphical Abstract.

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High efficient probes with Schiff base functional receptors for hypochlorite sensing under physiological conditions

Cited by 14 publications

References 28 publications

Research Progress of Small Molecule Fluorescent Probes for Detecting Hypochlorite

Research Progress of Small Molecule Fluorescent Probes for Detecting Hypochlorite

A Nontoxic, Bio‐friendly, Fluorescent Chemodosimeter for Hypochlorite Detection in Living Cells through the Oxidation of Hypochlorite on a Hydrazide System

Sensitive and Selective “Turn-On” Chemodosimetric Probes for Fe3+ Based on a Skeleton of 2-Hydroxy-1-Naphthaldehyde

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