A new coumarin based turn on fluorescent sensor (R1) was reported for the detection of highly hazardous Cd with excellent selectivity and sensitivity without any interference of other metal ions. The single crystal X-ray structure analysis of the sensor showed the actual geometry of the molecule. For the first time, a Cd induced FRET mechanism was observed and explained accordingly. Instant naked eye detection of Cd through a sharp colour change signified the practical applicability of R1. The sensor of high quantum yield was applied in the intracellular detection of poisonous Cd in living HeLa S3 cells.

A cell permeable FRET based platform for dual mode ‘naked-eye’in vitroandin vivodetection of Al3+over other common ions (including trivalent ions).

Herein, we introduce a new ratiometric 2,4,6-triamino-1,3,5-triazine-based probes (R1 and R2) having three different binding sites for three metal ion binder which can selectively detect Zn2+ ions and particularly the...

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A novel rhodamine-based chemosensor (R1) has been designed and synthesised for identifying Fe 3 + ions among different metal ions in aqueous medium. The sensitivity test has been carried out by using UV-vis and fluorescence methods taking mM concentration of R1 in HEPES buffer solution and the complexation has been described through fluorescence 'off-on' mecha-nism. Metallation of R1 was found to be tolerant with respect to tumor cells proliferation and viability of human peripheral blood mononuclear cells and RBC. It has also been demonstrated that the significant uptake of the chemosensor by the tumor cells was observed in cell imaging analysis.

Lead ion induced P-O bond breaking with instant colour change was observed in a tripodal hydroxyl-quinoline based phosphor-ester (). A new penta-coordinated lead chelate complex [Pb4HQ6(ClO4)2] was found. The hydrolysis reaction followed by P-O bond cleavage with 'Pb-O' and 'Pb-N' bond formation proved the chemodosimeter approach.

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A TBET based ‘turn-on’ fluorescent reagent with high Stokes shifts, exhibits selective and colorimetric detection of biologically important uric acid as well as toxic Hg2+.