High early patency of saphenous vein graft for coronary artery bypass harvested with surrounding tissue

Souza, Domingos; Bomfim, Vollmer; Skoglund, H; Dashwood, Michael R.; Borowiec, Jan; Bodin, Lennart; Filbey, Derek

doi:10.1016/s0003-4975(00)02508-x

Cited by 71 publications

(61 citation statements)

References 14 publications

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“…The early patency rate of the SV prepared by the "no touch" technique was very high (95.4%), even in grafts which had low flows [17]. To investigate if the pedicle of fat has importance in the improved patency of the saphenous grafts, we compared the angiographic results between the grafts from the "no touch" group with those treated by the conventional and intermediate techniques.…”

Section: Ci= Confidence Intervalmentioning

confidence: 99%

Preparation of the saphenous vein for coronary artery bypass grafting: a new technique "no touch" that maintains the vein wall integral and provides high immediate patency

Souza¹,

Dashwood²,

Tonazi³

et al. 2003

Rev Bras Cir Cardiovasc

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Preparation of the saphenous vein for coronary artery bypass grafting: A new technique -"no touch" -that maintains the vein wall integral and provides high immediate patency Preparo da veia safena na cirurgia de revascularização miocárdica: uma nova técnica -"no touch"-que mantém a parede da veia íntegra e proporciona uma alta perviabilidade imediata Method: A prospective randomized study in 156 patients who underwent CABG was performed comparing three SV harvesting techniques. The techniques were conventional (c) (adventitial stripping of the vein, manual distention and storing in saline solution); Intermediate (I) (after adventitial stripping, the vein was left in situ, covered with a papaverinesoaked compress, and stored in heparinized blood); and "no touch" (SV dissected with its surrounding tissue was left in situ, covered with a saline-soaked compress and stored in heparinized blood). A morphological study of the endothelium was preformed using scanning electronic microscopy and an angiographic assessment of the vein graft patency was performed at 18 months mean follow-up time. Also an immunohistochemistry assessment was performed to identify the enzyme, nitric oxide synthase (NOS) in the vein wall.Results: The preservation of the endothelial cell integrity was greater with the "no touch" technique than with the other procedures. At angiographic follow up, the patency for NT was 95.4%, 88.9% for grafts in group C and 86.2% for grafts in group I. The immunohistochemistry assessment revealed NOS in all three layers of the vein wall that was prepared by the "no touch" technique. However, a great reduction of this enzyme in veins treated by the conventional technique was observed. Conclusion:The endothelial integrity and NOS activity were better preserved when using the "no touch" technique for vein graft harvesting. The vasorelaxation and thromboresistant activities of nitric oxide (NO) may be responsible for the reduced of vasospasms and improved patency rate. Furthermore, the mechanical properties provided by the Rev Bras Cir Cardiovasc 2003; 18(4): 303-311

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Section: Ci= Confidence Intervalmentioning

confidence: 99%

Preparation of the saphenous vein for coronary artery bypass grafting: a new technique "no touch" that maintains the vein wall integral and provides high immediate patency

Souza¹,

Dashwood²,

Tonazi³

et al. 2003

Rev Bras Cir Cardiovasc

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“…Initial patency of SV treated with the NT technique was very high (95.4%) even in grafts with low blood flow 18 . To investigate whether the fat pedicle had a role in the improved patency of venous grafts, the angiographic results were compared between grafts treated with the NT technique and those treated with the I and C techniques.…”

Section: Discussionmentioning

confidence: 94%

Nova técnica cirúrgica de preparo da veia safena para revascularização do miocárdio sem manipulação direta - no-touch

Rueda

Souza

Lima

et al. 2008

Arq. Bras. Cardiol.

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“…Procedures to reduce this injury include in situ vein grafts and use of the no-touch surgical technique. 22,23 Venous injury upon inclusion within the arterial environment is caused by exposure to significant pulsatile stretch force, turbulent flow, and wall shear stress. Under normal physiologic conditions, veins exist as thin-walled, tubular structures permitting low flow in a low-pressure environment.…”

Section: Discussionmentioning

confidence: 99%

Photochemical Tissue Passivation Reduces Vein Graft Intimal Hyperplasia in a Swine Model of Arteriovenous Bypass Grafting

Goldstone

McCormack

Khan

et al. 2016

JAHA

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Background--Bypass grafting remains the standard of care for coronary artery disease and severe lower extremity ischemia. Efficacy is limited by poor long-term venous graft patency secondary to intimal hyperplasia (IH) caused by venous injury upon exposure to arterial pressure. We investigate whether photochemical tissue passivation (PTP) treatment of vein grafts modulates smooth muscle cell (SMC) proliferation and migration, and inhibits development of IH.

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High early patency of saphenous vein graft for coronary artery bypass harvested with surrounding tissue

Cited by 71 publications

References 14 publications

Preparation of the saphenous vein for coronary artery bypass grafting: a new technique "no touch" that maintains the vein wall integral and provides high immediate patency

Preparation of the saphenous vein for coronary artery bypass grafting: a new technique "no touch" that maintains the vein wall integral and provides high immediate patency

Nova técnica cirúrgica de preparo da veia safena para revascularização do miocárdio sem manipulação direta - no-touch

Photochemical Tissue Passivation Reduces Vein Graft Intimal Hyperplasia in a Swine Model of Arteriovenous Bypass Grafting

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