Herpes Simplex Virus Type 2 in the United States, 1976 to 1994

Fleming, Douglas T.; McQuillan, Geraldine M.; Johnson, Robert E.; Nahmias, André J.; Aral, Sevgi O.; Lee, Francis K.; Louis, Michael E. St.

doi:10.1097/00006254-199803000-00003

Cited by 174 publications

(249 citation statements)

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“…HSV infection is an important cofactor in the transmission of HIV. The majority of people with genital herpes are unaware that they are infected because they either have no symptoms or experience symptoms that neither they nor their physicians recognize as being due to herpes (Fleming et al 1997, Gupta et al 2007). …”

Section: Genital Herpesmentioning

confidence: 99%

Sexually Transmitted Diseases of the Vulva

Nwokolo

Barton

2009

Ridley's the Vulva

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Section: Genital Herpesmentioning

confidence: 99%

Sexually Transmitted Diseases of the Vulva

Nwokolo

Barton

2009

Ridley's the Vulva

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“…Die Seropräva-lenz steigt weltweit, in den USA wurde eine Zunahme in altersentsprechenden Gruppen um 25 innerhalb eines Zeitraums von 10 Jahren (1970-1980:1980-1990) beobachtet: 21 der Allgemeinbevölkerung der USA sind HSV-2+ [42]. Die Seroprävalenz von HSV-2-Infektionen bei Schwangeren variiert zwischen 7 (Tokio, 1988) und 33 (Stockholm, 1989; [17]). Ungefähr 1,2 Mio.…”

Section: Hsv-2unclassified

Infektionen mit Herpes-simplex- und Varicella-zoster-Viren in der Schwangerschaft

2006

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Primary infections with herpes simplex virus (HSV) and varicella-zoster virus (VZV) may lead to severe illness in pregnancy. Both diseases may be associated with transplacental virus transmission and fetal infection. Such infections can lead to intrauterine death, severe malformations and premature birth; the fetal/congenital varicella syndrome is well-defined. Herpes genitalis and varicella at the time of labor may lead to life threatening neonatal-herpes or varicella of the newborn. Currently neither active immunization nor neutralizing immunoglobulin is available for HSV infections. VZV-seronegative women in child-bearing age can be vaccinated and pregnant women exposed to VZV can be given specific immunoglobulins. While an infection is rarely blocked, the severity is generally reduced. For severe disease antiviral treatment is necessary, with valacyclovir and acyclovir represents the drugs of choice. Primary or recurrent overt disease of the genital tract at the time of delivery an indication for caesarean section. Suppression of recurrent genital herpes during the last weeks of pregnancy with valacyclovir and acyclovir reduces the need for surgical intervention. Neonates exposed to VZV should receive specific immunoglobulin. If neonates show signs of either infection, immediate treatment with acyclovir must be initiated.

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“…In den USA wurde im Rahmen von 2 großen Studien in der Zeit von 1976 und 1980 bzw. 1988 und 1994 ein Anstieg der HSV-2-Prävalenz um 30%, d. h. von 16% auf 21,9% beobachtet [12]. Der Anstieg betraf insbesondere weiße Frauen und Schwarze beiderlei Geschlechts.…”

Section: Erreger Und äTiopathogeneseunclassified

Herpes-simplex-Virusinfektionen

Gross

2004

Hautarzt

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The herpes simplex viruses type 1 and 2 (HSV 1 and 2) as typical members of the larger herpes virus group have the tendency to become latent after an inapparent primary infection. They are transmitted from person to person during episodes of reactivation. HSV 1 and 2 usually cause harmless mucosal infections. Usually HSV are kept in check by the immune system. An impaired immune response leads to HSV infections which can be life-threatening. Genital HSV infections are an important cause of genital ulcerations, and HSV 2 is a predisposing factor for HIV and AIDS. Worldwide the diagnostic possibilities for HSV are often inadequate. Despite the availability of modern chemotherapeutic agents, the treatment of HSV infections is in many cases less than satisfactory. Dermatologists play a major role in the early diagnosis and effective therapy of these infections. In this paper, the latest diagnostic and therapeutic, as well as prophylactic measures and vaccines, are reviewed.

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Herpes Simplex Virus Type 2 in the United States, 1976 to 1994

Cited by 174 publications

References 0 publications

Sexually Transmitted Diseases of the Vulva

Sexually Transmitted Diseases of the Vulva

Infektionen mit Herpes-simplex- und Varicella-zoster-Viren in der Schwangerschaft

Herpes-simplex-Virusinfektionen

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