Herpes Simplex Skin Lesions Simulating Smallpox

Herpes Simplex Virus

“…Muller et al (1972) described four cases where HSV infection presented as a widespread disseminated cutaneous problem and in some patients herpes resembled those cases seen in association with various dermatoses (see below). Similar cases have been described by other workers and appear to be particularly common in association with the haematological malignancies, particularly in the terminal phases (Lynfield et al 1969;Rendtorff and Fowinkle 1965;Smith and Melnick 1962;Solomon 1961). St Geme et al (1970) described the case of a 3-year-old-boy with Wiskott-Aldrich syndrome, who developed generalised disseminated herpes.…”