“…266 With later infections, the effects on the fetus are less severe and can include even a generalized vesicular eruption. 268 Generalized systemic HSV infection can result in infection of many organs and can cause marked hepatorenal necrosis, pancreas necrosis, encephalitis, and brain necrosis. 259,263 Finally, one must consider the various types of herpes that occur in immunocompromised patients.…”