Hepatoprotective activity of Amaranthus spinosus in experimental animals

Cytotoxic and apoptotic activities of extract of Amaranthus spinosus L. in Allium cepa and human erythrocytes

“…The plant extract possesses severe effects in hematology (Olufemi et al 2003). It shows immunomodulatory (Tatiya et al 2007), anthelmintic (Assiak et al 2002), analgesic (Krishnamurthi et al 2010), antidiabetic, antihyperlipidemic, spermatogenic (Girija and Lakshman 2011;Sangameswaran and Jayakar 2008), hepatoprotective (Zeashan et al 2008(Zeashan et al , 2009, anticancer (Cristine et al 2013), antioxidant (Odhavo et al 2007;Zeashan et al 2009) and chemoprotective activities . A. spinosus contains several active constituents like alkaloids, flavonoids, glycosides, phenolic acids, steroids, terpenoids, saponins, betalains, b-sitosterol, stigmasterol, rutin, catechuic tannins, etc.…”

Hepatoprotective effect of ethanol extract fromBerchemia lineateagainst CCl4-induced acute hepatotoxicity in mice

“…There is vast evidence indicating that herbal extracts from edible and medicinal plants exhibit strong antioxidant activity that could act against hepatic toxicity caused by various toxicants (Harish & Shivanandappa, 2006;Madureira et al, 2011;Upur et al, 2009;Yeh et al, 2012;Zeashan et al, 2008).…”

Amaranthus spinosusLinn. inhibits mast cell-mediated anaphylactic reactions

“…It is an annual or perennial herb native to tropical America and distributed throughout India (Senthil . According to Ayurveda (Indian traditional system of medicine) the plant is useful in conditions of bronchial asthma; it is also used as a digestive aide, laxative, diuretic, stomachic, and anti-pyretic, to improve appetite, biliousness, blood diseases, burning sensation, leprosy, bronchitis, rat bite, piles, and leucorrhoea, while the boiled leaves and root are given to children as a laxative, emollient, and poultice for abscesses, boils, and burns (Kirtikar and Basu, 1996;Zeashan et al, 2009a). In Malaysia, the plant is used as an expectorant and to relieve breathing in acute bronchitis (Ashok .…”

“…The tribal inhabitants like Bhils, Pardhis, Pawaras, Tadavis, and Wanjaris from Jalgaon district located on northern border of the state of Maharashtra, India uses decoction (15-20 ml) of whole plant in allergic bronchitis and asthma (Patil et al, 2008). A. spinosus has several biologically active constituents like alkaloids, flavonoids, glycosides, phenolic acids, steroids, amino acids, terpenoids, lipids, saponins, anthriquinone derivatives, volatile oils, organic acids, betalains, β-sitosterol, stigmasterol, linoleic acid, catechuic tannins, polyuronides, and carotenoids (Zeashan et al, 2009a).…”