Hemostasis and Thrombosis in Major Liver Resection

Abstract

The liver plays an important role in the balance between hemostasis and thrombosis. Hepatic resection, particularly when performed in the presence of underlying parenchymal liver disease, can cause perturbation of this balance. This review summarizes the changes that occur in normal hemostasis and thrombosis before, during, and after nontransplant hepatic resection and, wherever possible, provides strategies for the perioperative management of bleeding and thrombosis.

Chitosan Lactate Particles for Non-Compression Hemostasis on Hepatic Resection

“…Liver is an organ with extreme rich blood flow and fragile texture. Clinically, massive liver bleeding during surgical or traumatic injury [ 1 , 2 ] happens frequently and can be life-threatening. For example, diffuse bleeding over 2000 mL with life-threatening outcomes has been reported [ 3 ].…”

Thrombosis and Hemostasis Issues in Critically Ill Patients

“…11 The last three articles in this issue regard hemostasis and thrombosis issues in three frequently occurring clinical settings, that is, cardiac surgery, renal insufficiency, and renal replacement treatment, and major liver resection. [12][13][14] In these articles, recent insights in pathogenesis and clinical management are highlighted and potentially effective future treatment strategies are proposed.…”