Abstract:Effects of physical training in patients with type 2 diabetes mellitus: a systematic review Physical training is recommended in several studies and guidelines for the control of type 2 diabetes mellitus (DM2) and its complications. We performed a systematic review about the effects of aerobic training (AT), resistance (RT) or the combination of both (AT / RT), on glycated hemoglobin (HbA1c) in patients with DM2. Therefore, we included 15 clinical trials with at least 12 weeks duration about training program or… Show more
“…According to those findings, PA/exercise has a significant role in improvements of BG control, insulin sensitivity, and insulin resistance, reduction of BMI, HbA1c levels, and total cholesterol, etc. 72,100,111,132,133,[145][146][147][148][149][150][151][152] This section summarizes ( Table 1) the evidence about the role of PA/exercise on the control of T2DM.…”
Section: Management Of T2dmmentioning
confidence: 99%
“…169 Also, regular exercise modulates several intracellular pathways improving insulin resistance and glucose uptake in the skeletal muscle of T2DM individuals. 10 Yuing et al 150 15 Trials Physical training is associated with an increase in the peak or maximal oxygen uptake, exercise tolerance time, and muscle strength, and a reduction in HbA1c levels.…”
Section: The Physiological Effects Of Physical Activity In T2dmmentioning
confidence: 99%
“…156 Several studies have shown that PA also lowers the HbA1c levels. 79,95,111,119,132,133,136,142,143,[146][147][148][149][150][151][182][183][184] This means that the effect of an exercise on the decrement of BG levels could be evidenced by the reduction of the biomarkers of glycemic control which is HbA1c levels. The term HbA1c refers to a glycated hemoglobin or glycosylated hemoglobin.…”
Despite the improvements in clinical care of the patients, research updates, and public health interventions, there is still an increase in the prevalence, incidence, and mortality because of diabetes mellitus (DM). DM is a public health problem in both developed and developing countries. It has increased alarmingly, putting this disease in the dimension of an epidemic. Diabetes is associated with several complications which increase the risk of many serious health problems on the other side. Therefore, this review was aimed to discuss the antidiabetic effects of physical activity (PA) on type 2 DM (T2DM) by summarizing the significant studies on this topic. This review found that several studies have recommended the utilization of PA for the effective management of T2DM. PA is a non-pharmacologic therapy which is a significant strategy for the management of T2DM and is an appropriate lifestyle modification approach to be practiced by these patients. The studies showed that PA has antidiabetic effects which are evidenced by its substantial role in improving the blood glucose (BG) levels of the individuals with T2DM where it helps them to control their levels of glucose in the blood. It plays a significant role in glycemic control of this disease by lowering the BG levels through possible mechanisms such as decreasing insulin resistance, increasing production of glucose transporter type 4 (GLUT-4), lowering visceral adipose tissue (VAT), increasing pancreatic β-cell functions, using glucose for energy, and so on. In turn, the controlled glycemia helps to prevent the complications associated with uncontrolled T2DM and this would further improve the overall health of the patients and the burden on the health professionals as well. Finally, this review concludes that PA is the cornerstone in the management of T2DM. It also suggests that more attention is needed to its significance in the prevention, glycemic control, and its role in the management of the morbidity and mortality associated with T2DM. Practical PA recommendations and suggestions for the future direction of research in this area are also provided.
“…According to those findings, PA/exercise has a significant role in improvements of BG control, insulin sensitivity, and insulin resistance, reduction of BMI, HbA1c levels, and total cholesterol, etc. 72,100,111,132,133,[145][146][147][148][149][150][151][152] This section summarizes ( Table 1) the evidence about the role of PA/exercise on the control of T2DM.…”
Section: Management Of T2dmmentioning
confidence: 99%
“…169 Also, regular exercise modulates several intracellular pathways improving insulin resistance and glucose uptake in the skeletal muscle of T2DM individuals. 10 Yuing et al 150 15 Trials Physical training is associated with an increase in the peak or maximal oxygen uptake, exercise tolerance time, and muscle strength, and a reduction in HbA1c levels.…”
Section: The Physiological Effects Of Physical Activity In T2dmmentioning
confidence: 99%
“…156 Several studies have shown that PA also lowers the HbA1c levels. 79,95,111,119,132,133,136,142,143,[146][147][148][149][150][151][182][183][184] This means that the effect of an exercise on the decrement of BG levels could be evidenced by the reduction of the biomarkers of glycemic control which is HbA1c levels. The term HbA1c refers to a glycated hemoglobin or glycosylated hemoglobin.…”
Despite the improvements in clinical care of the patients, research updates, and public health interventions, there is still an increase in the prevalence, incidence, and mortality because of diabetes mellitus (DM). DM is a public health problem in both developed and developing countries. It has increased alarmingly, putting this disease in the dimension of an epidemic. Diabetes is associated with several complications which increase the risk of many serious health problems on the other side. Therefore, this review was aimed to discuss the antidiabetic effects of physical activity (PA) on type 2 DM (T2DM) by summarizing the significant studies on this topic. This review found that several studies have recommended the utilization of PA for the effective management of T2DM. PA is a non-pharmacologic therapy which is a significant strategy for the management of T2DM and is an appropriate lifestyle modification approach to be practiced by these patients. The studies showed that PA has antidiabetic effects which are evidenced by its substantial role in improving the blood glucose (BG) levels of the individuals with T2DM where it helps them to control their levels of glucose in the blood. It plays a significant role in glycemic control of this disease by lowering the BG levels through possible mechanisms such as decreasing insulin resistance, increasing production of glucose transporter type 4 (GLUT-4), lowering visceral adipose tissue (VAT), increasing pancreatic β-cell functions, using glucose for energy, and so on. In turn, the controlled glycemia helps to prevent the complications associated with uncontrolled T2DM and this would further improve the overall health of the patients and the burden on the health professionals as well. Finally, this review concludes that PA is the cornerstone in the management of T2DM. It also suggests that more attention is needed to its significance in the prevention, glycemic control, and its role in the management of the morbidity and mortality associated with T2DM. Practical PA recommendations and suggestions for the future direction of research in this area are also provided.
“…The population of Celaya with T2D, reported 74% of the participants doing mild physical activity. Yuing et al, In a meta-analysis show that physical activity, with monitoring and surveillance of patients with T2D, improves glycosylated hemoglobin levels [16]. It would be desirable that our patients with T2D perform more exercise with monitoring to improve their biochemical parameters and that their children who do not yet develop the disease, the exercise will probably cause their appearance to be delayed.…”
Objective: To determine the relationship of the perception of lifestyle with the level of physical activity in people with type 2 diabetes and without type 2 diabetes.
Study Design: Analytical cross-sectional observational study in Celaya, Guanajuato, Mexico.
Methodology: Sample composed of 100 people with type 2 diabetes and 100 people without type 2 diabetes, the lifestyle questionnaire and IPAQ questionnaire were used. Descriptive statistics were calculated for sociodemographic variables; it was calculated Chi-square test and Odds Ratio. To demonstrate the statistical significance of results, the value of P was set at .05. Statistical analysis was performed in STATA 13.0 ®.
Results: In patients with Type 2 Diabetes predominated females, married, who never went school and elementary and BMI ≥ 25 kg/m2; among patients without Type 2 Diabetes, predominant males, singles, went school or university, BMI ≥25 kg/m2; no relationship was found between lifestyle perception and level of physical activity in adults with type 2 diabetes (X² = 0.0022 gl 1 P = .96) neither it was found a significant relationship between lifestyle perception and level of physical activity in adults without type 2 diabetes (X² = 5.23 gl 1 P = .02 RM = 2.85 95% CI = 0.80 to 10.4).
Conclusion: The results show that self-perception of lifestyle and physical activity is different in people with less age, more schooling, males.
“…[20] A systematic review aimed to evaluate the effect of different types of exercise on glycated hemoglobin in patients with diabetes and showed a reduction in HbA1c levels in all training groups, without differences between them. [21] The practice of physical activity proved to be an important intervening factor for good glycemic control and consequent better adherence to treatment. Physical activity is one of the pillars of diabetes treatment, as it has a significant impact on improving glycemic control and preventing associated complications and comorbidities.…”
Adherence is a key factor for the treatment of chronic conditions, especially if different drug administration routes are needed. This study aimed to analyze factors associated with adherence to pharmacological treatment in patients with type 2 diabetes. A cross-sectional study was carried out with 173 patients with type 2 diabetes, using a questionnaire with sociodemographic and clinical variables and the Morisky-Green Scale. Multivariate statistics were used. The results show that the female gender (69.4%), elderly (59.5%), low education (62.4%), and ten years or more years of diagnosis (67.1%) predominated in the sample. People over 60 years old were more likely to adhere to treatment than young adults (OR: 2.57). Those who performed physical activities were more likely to accept treatment than sedentary subjects (OR: 2.04). In conclusion, the study shows a significant association between adherence to pharmacological treatment and the variables age over 60 and physical activity practice.
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