Hemoglobin A1c Versus Oral Glucose Tolerance Test in Postpartum Diabetes Screening

Picón-César, María José; Murri, Mora; Muñoz, Araceli; Fernández‐García, José Carlos; Gómez‐Huelgas, Ricardo; Tinahones, Francisco J.

doi:10.2337/dc11-2111

Cited by 107 publications

(78 citation statements)

References 24 publications

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“…It is acknowledged that this recommendation is largely based on expert opinion or common clinical practice [8,49]. Measurement of HbA 1c does not seem to perform well for this group of women [50].…”

Section: Risk Factors For Diabetes and Gdm • Previous Gestational Diamentioning

confidence: 99%

A proposal for the use of uniform diagnostic criteria for gestational diabetes in Europe: an opinion paper by the European Board & College of Obstetrics and Gynaecology (EBCOG)

et al. 2015

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Screening and diagnostic criteria for gestational diabetes (GDM) are inconsistent across Europe, and the development of a uniform GDM screening strategy is necessary. Such a strategy would create opportunities for more women to receive timely treatment for GDM. Developing a consensus on screening for GDM in Europe is challenging, as populations are diverse and healthcare delivery systems also differ. The European Board & College of Obstetrics and Gynaecology (EBCOG) has responded to this challenge by appointing a steering committee, including members of the EBCOG and the Diabetic Pregnancy Study Group (DPSG) associated with the EASD, to develop a proposal for the use of uniform diagnostic criteria for GDM in Europe. A proposal has been developed and has now been approved by the Council of the EBCOG. The current proposal is to screen for overt diabetes at the first prenatal contact using cut-off values for diabetes outside pregnancy, with particular efforts made to screen high-risk groups. When screening for GDM is performed at 24 weeks' gestation or later, the proposal is now to use the 75 g OGTT with the new WHO diagnostic criteria for GDM. However, more research is necessary to evaluate the best GDM screening strategy for different populations in Europe. Therefore, no clear recommendation has been made on whether a universal one-step, two-step or a risk-factorbased screening approach should be used. The use of the same WHO diagnostic GDM criteria across Europe will be an important step towards uniformity.

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Section: Risk Factors For Diabetes and Gdm • Previous Gestational Diamentioning

confidence: 99%

A proposal for the use of uniform diagnostic criteria for gestational diabetes in Europe: an opinion paper by the European Board & College of Obstetrics and Gynaecology (EBCOG)

et al. 2015

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“…In our study, the CHOC had a higher content of sugar compared with the AAD and ALD, whereas other studies24, 36 compared the effects of consumption of dark chocolate with white chocolate that contained a similar amount of sugar and no flavanols. Furthermore, fasting glucose and insulin were measured after each treatment period in the present study, whereas the previously mentioned studies used an oral glucose tolerance test that showed a greater sensitivity than glycosylated hemoglobin and fasting glucose 37. Furthermore, participants in the current study had a normal glucose level at baseline, whereas studies with positive findings included participants with pre–diabetes mellitus27 or type 2 diabetes mellitus,7 which may account for discrepancies between studies.…”

Section: Discussionmentioning

confidence: 83%

Effects of Dark Chocolate and Almonds on Cardiovascular Risk Factors in Overweight and Obese Individuals: A Randomized Controlled‐Feeding Trial

Lee

Berryman

West

et al. 2017

JAHA

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BackgroundConsumption of almonds or dark chocolate and cocoa has favorable effects on markers of coronary heart disease; however, the combined effects have not been evaluated in a well‐controlled feeding study. The aim of this study was to examine the individual and combined effects of consumption of dark chocolate and cocoa and almonds on markers of coronary heart disease risk.Methods and ResultsA randomized controlled, 4‐period, crossover, feeding trial was conducted in overweight and obese individuals aged 30 to 70 years. Forty‐eight participants were randomized, and 31 participants completed the entire study. Each diet period was 4 weeks long, followed by a 2‐week compliance break. Participants consumed each of 4 isocaloric, weight maintenance diets: (1) no treatment foods (average American diet), (2) 42.5 g/d of almonds (almond diet [ALD]), (3) 18 g/d of cocoa powder and 43 g/d of dark chocolate (chocolate diet [CHOC]), or (4) all 3 foods (CHOC+ALD). Compared with the average American diet, total cholesterol, non–high‐density lipoprotein cholesterol, and low‐density lipoprotein cholesterol after the ALD were lower by 4%, 5%, and 7%, respectively (P<0.05). The CHOC+ALD decreased apolipoprotein B by 5% compared with the average American diet. For low‐density lipoprotein subclasses, compared with the average American diet, the ALD showed a greater reduction in large buoyant low‐density lipoprotein particles (−5.7±2.3 versus −0.3±2.3 mg/dL; P=0.04), whereas the CHOC+ALD had a greater decrease in small dense low‐density lipoprotein particles (−12.0±2.8 versus −5.3±2.8 mg/dL; P=0.04). There were no significant differences between diets for measures of vascular health and oxidative stress.ConclusionsOur results demonstrate that consumption of almonds alone or combined with dark chocolate under controlled‐feeding conditions improves lipid profiles. Incorporating almonds, dark chocolate, and cocoa into a typical American diet without exceeding energy needs may reduce the risk of coronary heart disease.Clinical Trial RegistrationURL: https://www.clinicaltrials.gov. Unique identifier: NCT01882881.

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“…Bu konuda yapılmış çalışmalarda GDM sonrası DM gelişim sıklığı %6,06 ile %34,6 arası değişmektedir (7,8).…”

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Evaluation of Metabolic Parameters of Gestational Diabetic Patients in Postpartum Period

Türker¹,

Türker²,

Ahbab³

et al. 2018

Haseki

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ÖzAmaç: Gestasyonel diabetes mellitus (GDM) postpartum dönemde tip 2 DM gelişimi ve metabolik disfonksiyon için yüksek risk faktörüdür. Bu sebeple biz gestasyonel diyabetik hastaların postpartum dönemde metabolik parametrelerini değerlendirdik.Yöntemler: 2011-2014 yılları arasında, Haseki Eğitim ve Araştırma Hastanesi Kadın Hastalıkları ve Doğum Polikliniği'nde 24. gebelik haftasında açlık ve tokluk plazma kan glikozu yüksek tespit edilerek oral glikoz tolerans testi uygulanıp, GDM tanısı konularak endokrinoloji polikliniğine yönlendirilmiş olan 40 hasta 05 Mart 2014 tarih ve karar no: 91 sayılı etik kurul onayı alınarak postpartum dönemde çalışmaya alındı. Hastalar altıncı aydan başlayarak kontrole çağırıldı ve boy, kilo, beden kitle indeksi (BKİ), ölçümsel parametreleri değerlendirildi. Ek olarak, hemoglobin A1c (HbA1c), açlık kan glikozu, tokluk kan glikozu, insülin, lipid profili, üre, kreatinin, spot idrarda protein/kreatinin parametrelerine bakıldı. Bulgular: Takip edilen periyotta yedi hastada postpartum DM gelişti (%17,5). Postpartum diyabetik hastalarda ortalama açlık kan glikoz düzeyi ve HbA1c değerleri anlamlı olarak yüksek bulundu (p=0,001; p=0,005). Ortalama BKİ, bel çevresi, trigliserid düzeyleri iki grup arasında benzer bulundu (p=0,521, p=0,607, p=0,240).Sonuç: Gestasyonel diyabetik hastalarda gebelik sonrası DM gelişimi açısından kesin bir bulguya rastlanmadı. Ancak GDM, postpartum DM gelişimi için risk faktörüdür.Anahtar Sözcükler: Diabetes mellitus, gestasyonel diabetes mellitus, metabolik parametreler Aim: Gestational diabetes mellitus (GDM) is associated with an increased risk for type 2 DM and metabolic dysfunction after pregnancy. Therefore, we aimed to evaluate the metabolic parameters in women with a history of GDM Methods: In this study, we included a total of 40 patients with high fasting and postprandial glucose levels and abnormal oral glucose tolerance test at 22-28 weeks of pregnancy who attended the endocrinology outpatient clinic between 2011 and 2014. We evaluated the metabolic parameters, weight, height and body mass index (BMI) at six months postpartum. In addition, fasting and postprandial glucose, insulin, hemoglobin A1c (HbA1c), urea, and creatinine levels, spot urine protein-to-creatinine ratio, and lipid profile were analyzed.Results: Postpartum DM was detected in seven patients (17.5%) in the follow-up period. Mean fasting glucose level and HbA1c values were statistically significantly higher in subjects with postpartum diabetes (p=0.001, p=0.005, respectively). Mean BMI, waist circumference, and triglyceride levels were similar between those with and without postpartum diabetes (p=0. 521, p=0.607, p=0.240, respectively) Conclusion: In our study, there was no finding predicting postpartum DM in patients with GDM, however, GDM increases the risk of postpartum DM. Keywords GirişDiabetes mellitus (DM), çeşitli etiyolojik nedenlerle insülin hormonu sekresyonunun ve/veya insülin hormonu etkisinin eksikliği sonucu karbonhidrat, protein ve yağ metabolizmasında bozukluklara ...

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Hemoglobin A1c Versus Oral Glucose Tolerance Test in Postpartum Diabetes Screening

Cited by 107 publications

References 24 publications

A proposal for the use of uniform diagnostic criteria for gestational diabetes in Europe: an opinion paper by the European Board & College of Obstetrics and Gynaecology (EBCOG)

A proposal for the use of uniform diagnostic criteria for gestational diabetes in Europe: an opinion paper by the European Board & College of Obstetrics and Gynaecology (EBCOG)

Effects of Dark Chocolate and Almonds on Cardiovascular Risk Factors in Overweight and Obese Individuals: A Randomized Controlled‐Feeding Trial

Evaluation of Metabolic Parameters of Gestational Diabetic Patients in Postpartum Period

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