Hemochromatosis: diagnosis and quantification of liver iron with gradient-echo MR imaging.

Abstract

This method, which can be improved by using more sensitive sequences with a high-field-strength system, should be competitive with biopsy for the diagnosis of substantial liver iron overload.

A Pitfall in Assessing Gastric Lymphoma after Eradication ofHelicobacter pylori

“…4 The recommendation against the use of synthetic ethinyl estradiol, a modification of the principal human estrogen, seems to relate to potency; however, much lower doses of ethinyl estradiol than those used in contraceptives (e.g., 2.5 to 10 m g) are available for pubertal induction and are being studied for their effect on postmenopausal osteoporosis. 5 Such low doses may be more physiologic for inducing puberty than those recommended by Dr. Saenger. …”

“…The report concludes that early estrogen replacement cannot be justified on the basis of bone mineral status. 5 As Gargan and Peerzada point out, we need a national data base. The U.S. Turner Syndrome Society (1313 S.E.…”

“…3 Although these results are general and cannot guide management in the case of patients with recurrent thrombosis or families that appear to be extremely prone to thrombosis, they are reassuring and do not support the use of prophylactic anticoagulation solely on the basis of the presence of the biochemical defect, especially in the light of the known risks of the therapy (a 1 to 3 percent risk of major hemorrhage per year and a 0.3 to 0.6 percent risk of fatal hemorrhage per year). 4,5 On the basis of these retrospective data, we believe that asymptomatic patients with heritable thrombophilia should not receive anticoagulant agents except in situations in which the risk of thrombosis is increased -for example, after surgery and during immobilization. …”

“…Others have drawn the same conclusion, 2,3 including both the Second and Ninth Circuit Courts of Appeals. 4,5 In addition, the Catholic Church, in its Charter for Health Care Workers, 6 approved by the Congregation for the Doctrine of the Faith, states, "The administration of food and liquids, even artificially, is part of the normal treatment always due to the patient . .…”

“…The Ninth Circuit Court has already ruled that a proxy's decision is the same as the patient's decision, 5 and there is precedent for allowing involuntary euthanasia by dehydration at a proxy's request. 7 Where will the slippery slope end?…”