Hematological profile of patients with type 2 diabetic mellitus in El-Beida, Libya

Abstract

Objectives: The objective of this study is to help identify the hematological profile of patients with diabetes Settings: The study was conducted at El-Beida Hospital, El-Beida City, Libya. Subjects and Methods: The study subjects selected for this study consist of 103 Libyan type 2 diabetic patients (79 males + 24 females) and 39 healthy non-diabetic subjects (29 males and 10 females) acted as controls. They were matched for age (56.1 ± 7.8 years vs. 55.0 ± 6.3 years. The hematocrit value (HCT), hemoglobin content, red blood cells count (RBCs) and mean corpuscular volume (MCV) concentration with increased white blood cells counts (WBCs), mean erythrocyte hemoglobin concentration (MCHC), mean corpuscular hemoglobin (MCH), lymphocytes and neutrophils levels were performed. Results: Hematological studies in the diabetic patients showed significantly lower HCT values, hemoglobin content, RBCs count and MCV concentration than in the controls. Greater total WBC counts, MCHC concentrations, MCH, lymphocytes and neutrophils counts were observed in the patients than in the controls. No differences were found between platelets counts in the diabetic patients and the control. Conclusions: Significant aberrations in some hematological parameters associated with carbohydrate, protein and lipid metabolisms was identified in this selected group of people with diabetes.

White blood cells and platelet profiles of diabetic patients at University of Gondar specialized referral hospital: A comparative cross‐sectional study

“…41 In the present study, WBC indices (WBC count, lymphocyte, and mixed number) increased significantly in the DM patients compared with the control group. This study supports the finding of previous studies conducted in Libya, 42 Ethiopia, 43 India, 44 Nigeria, 45 Bangladesh, 46 and Turkey. Alteration in WBC indices has also been reported in DM patients.…”

Red Blood Cell Parameters and Their Correlation with Glycemic Control Among Type 2 Diabetic Adult Patients in Eastern Ethiopia: A Comparative Cross-Sectional Study

“…The mean RBC count, Hct, and Hgb values were significantly lower in T2DM patients than in the control group. This finding is in harmony with reports from India, 28 Libya, 29 Sudan, 30 and Ethiopia. 20 , 21 The relative decrease in RBCs count, Hct, and Hgb level might be that long-term hyperglycemia causes the generation of free oxygen radicals and irreversible glycation of hemoglobin and RBC membrane proteins.…”

Haematological profile of diabetes and non-diabetes patients in rural tertiary centre

“…Patients and controls were well matched for age and gender distribution. 12 Present study showed that diabetics had mean hemoglobin of 11.17±4.42 (g/dl) and non-diabetics 14.11±3.46 (g/dl). In diabetics mean haemoglobin, RBCs, PCV, and MCV was significantly lower than in nondiabetics.…”

“…Similar observations were made by Al Salhen KS et al in T2DM had lower haemoglobin concentrations. 12 In T2DM patient's PCV, whole blood haemoglobin, RBCs and MCV values were significantly lower than in controls with percent differences of 27.7, 19.2, 23.5 and 5.4%, respectively. The mean values for MCHC and MCH were also significantly greater in diabetic patients than healthy controls.…”