2002
DOI: 10.1590/s0102-09352002000100002
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Abstract: The course of experimental T. evansi infection in four dogs was followed for 82 days and hematological, biochemical and anatomopathological findings were studied. Infected animals showed progressive decrease in red blood cell count and hemoglobin concentration, leading to anemia which persisted from the third week post-infection until the end of the study. Leucopenia and neutropenia were observed between weeks 2 and 5 of the infection. The infected dogs developed hyperproteinemia and a decrease in the albumin:… Show more

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Cited by 59 publications
(20 citation statements)
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“…Observed reduced serum albumin levels were may be due to decreased liver biosynthesis and progressive loss of albumin in urine [4]. Due to tissue damage and kidney dysfunction, uremia and elevated creatinine levels were noticed in the present study [8]. Diminazene aceturate is the commonly used drug to control trypanosomosis in animals in Africa which have been in use for over 40 years [9].…”
supporting
confidence: 52%
“…Observed reduced serum albumin levels were may be due to decreased liver biosynthesis and progressive loss of albumin in urine [4]. Due to tissue damage and kidney dysfunction, uremia and elevated creatinine levels were noticed in the present study [8]. Diminazene aceturate is the commonly used drug to control trypanosomosis in animals in Africa which have been in use for over 40 years [9].…”
supporting
confidence: 52%
“…It has been suggested that the drop in albumin levels on its own is a compensatory mechanism for maintaining blood viscosity, which is increased by hyperglobulinemia (57). …”
Section: Eloy Lj and Lucheis Sb Canine Trypanosomiasis: Etiology Of mentioning
confidence: 99%
“…O desvio a esquerda (pico de bastonetes) no dia 35 deixa claro que a mobilização de células imaturas na circulação foi devido a uma provável demanda tecidual em resposta inflamatória e responsiva a infecção pelo flagelado, porém não tendo relação com o número de parasitos circulante, mas sim com as alteraçoes clinicas de edema de face, emagressimento progressivo e aumento da temperatura. Cães infectados experimentalmente com T. evansi podem ter leucopenia e neutropenia (AQUINO et al 2002) ou nao ter alteração referente ao leucograma (RUE et al, 2000). Isto mostra que o leucograma de animais infectados por T. evansi pode variar, pois cães apresentam redução dos leucocitos circulantes, enquanto os gatos apresentam aumento destas células, semelhante ao que ocorrre em cobaios e equinos VILLAVICENCIO;ROUX, 1991;RODRIGUES et al, 2005).…”
Section: Resultsunclassified
“…Em equinos, camelos, cães, coelhos e roedores a infecção por T. evansi leva a alterações como oscilações entre leucocitose e leucopenia, linfocitose e linfopenia durante a parasitemia (JATKAR; PUROHIT, 1971;AQUINO et al, 2002;RODRIGUES et al, 2005). No modelo felino não foi avaliado, até a presente data, o leucograma de animais infectados pelo T. evansi, assim, o presente trabalho tem como objetivo de investigar alterações no leucograma de felinos domésticos infectados experimentalmente pelo T. evansi, relacionando estas alterações com a parasitemia.…”
Section: Introductionunclassified