Hematologic and biochemical abnormalities in athletic horses

Ricketts, S. W.

doi:10.1016/b978-0-7020-2671-3.50047-7

Cited by 13 publications

(11 citation statements)

References 45 publications

(72 reference statements)

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“…However their values returned to the stall values within 24 or 48 hours post exercise, in accordance with other studies conducted on sport horses (Piccione et al, 2010b;Padalino et al, 2007;Kingston, 2004a). The increase in RBC, Hct and Hgb can be attributed mainly to reflex splenic contractions, which occur in horses in response to fright, excitement, and exercise (Ricketts, 2004).…”

Section: Discussionsupporting

confidence: 80%

Plasma malondialdehyde, biochemical and haematological parameters in standardbred horses during a selected field exercise test

Jagric-Munih¹,

Nemec-Svete²,

Zrimšek³

et al. 2012

Acta vet (Beogr)

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The aim of the present study was to determine changes in plasma malondialdehyde (MDA) concentration and haematological and biochemical profiles in 10 clinically healthy standardbred horses subjected to a selected field exercise test. Correlations between plasma MDA, the main lipid peroxidation end-product, and muscle enzymes: creatine kinase (CK) and aspartate aminotransferase (AST) were determined in serum samples. Venous blood samples for determination of selected blood parameters were collected, immediately post exercise, and 24 and 48 hours post exercise.Significant changes in most of the biochemical and haematological parameters determined immediately after exercise reflect the normal physiological response of horses to a selected field exercise test. Most of these parameters returned to or close to the stall values within 48 hours. The concentration of plasma MDA increased immediately post exercise, though not significantly; however it increased significantly 24 hours post exercise and reached its highest value 48 hours post exercise. Thus exercise-induced oxidative stress is evidenced by increased lipid peroxidation. From the rapid decline of serum CK activity post exercise and the absence of significant correlations between MDA and serum muscle enzymes, we concluded that the selected field exercise test caused no permanent alteration in muscle cell integrity or muscle damage.

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Section: Discussionsupporting

confidence: 80%

Plasma malondialdehyde, biochemical and haematological parameters in standardbred horses during a selected field exercise test

Jagric-Munih¹,

Nemec-Svete²,

Zrimšek³

et al. 2012

Acta vet (Beogr)

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“…Plasma lactate was measured as an indicator of muscle fatigue and fitness (Ricketts, 2004;Rainger et al, 1995). At both trials plasma lactate concentrations remained within reference ranges reported in literature (Stull and Rodiek, 2000;Rainger et al, 1995;Lumsden et al, 1980) at all three sampling phases, which indicates no muscular fatigue due to transport and work.…”

Section: Behaviour Changesmentioning

confidence: 94%

“…Significantly lower values at Trial II might be ascribed to calmative effects. Namely, reflex splenic contractions occur in horses in response to fright, excitement, and exercise, thus increasing the numbers of young macrocytic erythrocytes in the circulating pool (Ricketts, 2004). This might explain significantly higher MCV values in untreated horses.…”

Section: Behaviour Changesmentioning

confidence: 98%

Influence of a calmative on selected blood parameters in horses under stressful conditions

Nemec-Svete¹,

Čebulj‐Kadunc²,

Kruljc³

2008

Acta vet. (Beogr.)

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The results of few studies on tryptophan supplementation conducted in horses are contradictory and none of these studies have shown that tryptophan is an effective calmative in horses. The objective of the present study was to determine changes in hematological parameters, plasma lactate, serum cortisol and biochemical profile, as well as the behavior of untreated and calmative treated horses under stressful conditions in order to determine the effects of the applied calmative. The study also aims to confirm the importance of a 24 hour rest after work. The same six horses were on duty twice, Trial I and Trial II, under stressful conditions. Blood samples were collected three times, at pretransport, post-stress and resting phase. Horses' behavior was observed carefully by the riders. The study showed that most changes of the hematological and biochemical profiles reflect the response to exercise as horses were physically active while being on duty. The effect of the calmative is mainly reflected by a minor extent of changes of measured parameters, as determined by comparison at individual sampling phases. According to the observations of horses' behavior, we may conclude that the use of calmatives did calm the horses. The study confirmed that horses need at least 24 hours of rest after working

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“…43.4). 5 Although lactate dehydrogenase activity is often measured in serum biochemical panels, it has a low degree of tissue specificity without isoenzyme measurement. 3 In horses, the LDH-5 isoenzyme is derived largely from muscle and liver tissue, and therefore increases can be interpreted similar to increases in AST activity if this specific isoenzyme fraction is analyzed.…”

Section: Muscle Enzyme Activitiesmentioning

confidence: 99%

“…[3][4][5] Alterations in SPE morphology associated with a variety of pathologic conditions have been described in horses. 4,5 In general, however, this procedure has limited diagnostic value and should be utilized in conjunction with additional diagnostics appropriately tailored to the clinical signs or disease process of concern. 3 Simple quantitative measurement of total protein and albumin concentrations in performance horses can provide useful information regarding infectious or parasitic disease.…”

Section: Introductionmentioning

confidence: 99%

Biochemical abnormalities of athletic horses

McKenzie¹

2014

Equine Sports Medicine and Surgery

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Hematologic and biochemical abnormalities in athletic horses

Cited by 13 publications

References 45 publications

Plasma malondialdehyde, biochemical and haematological parameters in standardbred horses during a selected field exercise test

Plasma malondialdehyde, biochemical and haematological parameters in standardbred horses during a selected field exercise test

Influence of a calmative on selected blood parameters in horses under stressful conditions

Biochemical abnormalities of athletic horses

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