SRAM-based FPGAs are becoming increasingly attractive for use in space applications due to their reconfigurability and signal processing capabilities, as well as their increasing speed and capacity. Traditional SRAM-based FPGAs, however, are highly sensitive to the ionizing radiation environment in space, making them prone to radiation-induced memory upsets. In this paper, we evaluate and compare scrubbing techniques for Xilinx SRAM-based FPGAs with respect to radiation-induced single event upsets. A test framework using an exchangeable payload is developed for this purpose and run on a Xilinx Virtex-5 FPGA. We show that recent SRAM-based FPGAs can constitute a cost-efficient alternative to radiation-hardened or antifuse FPGAs for non-critical space application such as satellite instruments.