Heart transplantation from cardiac arrest-resuscitated donors

Попцов, В. Н.; Спирина, Е. А.; Пчельников, В. В.; Khatutskii, V. M.; Алиев, Э. З.; Воронков, В. Ю.; Насипова, Л. Р.; Епремян, А. С.; Золотова, Е. Н.; Скокова, А. И.; Агасян, П. М.

doi:10.15825/1995-1191-2019-2-23-30

RJTAO

2019

DOI: 10.15825/1995-1191-2019-2-23-30

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Heart transplantation from cardiac arrest-resuscitated donors

В. Н. Попцов

Е. А. Спирина

В. В. Пчельников

et al.

Abstract: Трансплантация сердца от доноров, перенесших сердечно-легочную реанимацию (СЛР) в процессе кондиционирования, является одним из вариантов увеличения доступности трансплантации сердца (ТС). В исследование включили 28 реципиентов: 25 (89,3%) мужчин и 3 (10,7%) женщины, возраст от 20 до 68 (46,2 ± 13,7) лет, которым в ФГУ «ФНЦТиИО им. академика В.И. Шумакова» в период с 01.01.2011 г. по 31.12.2017 г. была выполнена ТС от доноров, перенесших СЛР, что составило 4,0% от общего числа ТС за анализируемый период (n = 6… Show more

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Modern ideas in heart donor selection criteria

Тенчурина

Минина

2020

RJTAO

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With the limited capacity of the available donor pool and the simultaneously growing demand for heart transplantation, expanding the heart donor selection criteria as one of the ways of increasing the availability of organ transplantation, and particularly donor heart, has become a challenge. On one hand, the use of expanded criteria donors increases the number of transplants and reduces the time spent on the waiting list. On the other hand, however, it increases the risk of adverse transplant outcomes. Accordingly, high-risk donors require a more thorough objective assessment using predictive models, while organs obtained from expanded criteria donors, require optimal selection of a donor-recipient pair. Analysis of global and national studies presented in this review reveals the depth of the current problem of heart donor selection.

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Modern ideas in heart donor selection criteria

Тенчурина

Минина

2020

RJTAO

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Organizational, medical and epidemiological prerequisites for reviewing donor criteria in heart transplantation

Тенчурина

Минина

2020

RJTAO

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Organ donation and transplantation in Moscow have witnessed changes in the last decade. These changes have led not only to quantitative growth in the number of effective donors but also to fundamentally new (for Russian medical practice) characteristics of the donor pool. As a result, the selection criteria for organ donors have undergone some radical revisions. Objective: to analyze the medical and epidemiological characteristics of the pool of effective heart donors and assess their impact on selection of heart transplants. Materials and methods. In our study, we used the medical and epidemiological data of 650 brain-dead donors whose organs were procured from January 1, 2012 to December 31, 2017. Results. During the study period, the number of effective heart donors in Moscow increased from 4.4 (2012) to 11.2 (2017) per million population per year. The medical and epidemiological characteristics of the total pool of donors and the pool of heart donors underwent major changes. Among effective heart donors, there was a dynamic increase in the average age from 38.4 to 47 years, predominance of a proportion of donors with stroke 38.2 (2012) vs 83.2 (2017) and, accordingly, an increase in the frequency of such comorbid conditions, as hypertension and diabetes. Conclusion. The results presented in the study indicate a growing practice of working with expanded criteria donors. This practice is most effectively developed in the field of heart transplantation than in transplantation of other extrarenal organs. Undoubtedly, the experience under study is unique and relevant not only for the Russian Federation, but also for the world of transplantology, as it allows to provide vital assistance to patients with end-stage heart failure within a reasonable timeframe.

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Heart transplantation from cardiac arrest-resuscitated donors

Cited by 2 publications

References 19 publications

Modern ideas in heart donor selection criteria

Modern ideas in heart donor selection criteria

Organizational, medical and epidemiological prerequisites for reviewing donor criteria in heart transplantation

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