Health-related quality of life in patients with chronic respiratory failure after long-term mechanical ventilation

Euteneuer, Sara; Windisch, Wolfram; Suchi, Stefan; Köhler, Dieter; Jones, Paul; Schönhofer, Bernd

doi:10.1016/j.rmed.2005.06.008

Cited by 44 publications

(46 citation statements)

References 38 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Therefore, one could speculate that invasive HMV provides a sense of security at least in some severely disabled NMD patients with advanced chronic respiratory failure. Furthermore, patients with chronic respiratory failure following prolonged weaning (and also suffering from NMD), who were not dependent on HMV, had similar HRQL scores to patients with chronic respiratory failure who had electively received HMV in the form of long-term NIV [23]. …”

Section: Discussionmentioning

confidence: 99%

Invasive Home Mechanical Ventilation: Living Conditions and Health-Related Quality of Life

2015

Self Cite

View full text Add to dashboard Cite

Background: The number of patients with invasive home mechanical ventilation (HMV) following unsuccessful weaning is steadily increasing, but little is known about the living conditions and health-related quality of life (HRQL) in these patients. Objectives: To establish detailed information on living conditions and HRQL in patients with invasive HMV. Methods: The Severe Respiratory Insufficiency Questionnaire (SRI) was used to measure specific HRQL aspects in addition to patient interviews on individual living conditions during home visits. Results: Thirty-two patients with lung disease, most prominently COPD (n = 18), and neuromuscular disorders (n = 14) were included. The overall mean SRI summary scale score (range 0-100) was 53 ± 16, with a broad range amongst individuals (23-86). Neuromuscular patients were younger than those with lung diseases (49 ± 18 vs. 67 ± 11 years; p < 0.005), and although they had a higher nursing dependency and fewer comorbidities, they tended to have higher (better) SRI summary scale scores (58 ± 16 vs. 48 ± 15; p = 0.092). Living in a private home compared to living in nursing facilities did not influence the SRI scores. Conclusions: Patients undergoing invasive HMV primarily following unsuccessful weaning reported an individual HRQL which, when taken together, was highly heterogeneous and ranged from very good to extremely bad. Older patients with COPD and more comorbidities are likely to have a worse HRQL than neuromuscular patients, while the living situation does not influence the HRQL.

show abstract

Section: Discussionmentioning

confidence: 99%

Invasive Home Mechanical Ventilation: Living Conditions and Health-Related Quality of Life

2015

Self Cite

View full text Add to dashboard Cite

show abstract

“…In the study by Euteneuer et al (2006), QOL was found to be worse in patients with chronic obstructive pulmonary disease (COPD) and neuromuscular diseases, but not in patients with restrictive ventilatory disorders. These results are partly similar to ours, because there was no difference between QOL in patients having restrictive PFT pattern and those having normal PFT pattern despite QOL was worse in AS patients than controls.…”

Section: Discussionmentioning

confidence: 99%

The Pulmonary Involvement in Rheumatic Diseases: Pulmonary Effects of Ankylosing Spondylitis and Its Impact on Functionality and Quality of Life

Dinçer

Çakar

Kıralp

et al. 2007

Tohoku J. Exp. Med.

View full text Add to dashboard Cite

Rheumatic diseases are chronic inflammatory diseases which cause mild to severe functional loss and disability due to articular and extra-articular manifestations. One common form -ankylosing spondylitis (AS)-affects mainly the axial skeleton and sacroiliac joints, and certain extra-articular organs. The pulmonary involvement is a known manifestation of AS and emerges either in the form of interstitial lung disease or in the form of restricted pulmonary functions. The aim of this study is to determine the pulmonary functions in AS patients and to assess its relationship with quality of life, functionality and disease activity. Thirty-six AS patients and 34 healthy volunteers were recruited for the study. A detailed examination, pulmonary function tests, smoking inquiry and quality of life questionnaire were performed on all participants. Also patients were requested to complete functionality and disease activity indexes. The outcomes showed that 15 (41.7%) AS patients had pulmonary involvement: twelve patients with restrictive patterns, one with obstructive pattern, and two with both restrictive and obstructive patterns. Decreased forced expiratory volume in one second was associated with deteriorated functionality ( p < 0.05). Decreased chest expansion was also accompanied with decreased forced vital capacity ( p < 0.05). There was no statistically significant difference between the smoking and non-smoking patients in regard to disease activity, functionality and pulmonary function test variables ( p > 0.05). In conclusion, the pulmonary involvement is common in AS and might have disturbed functionality and the quality of life in AS patients. rheumatic disease; ankylosing spondylitis; pulmonary involvement; functionality; quality of life

show abstract

“…This instrument has successfully been used to evaluate HRQoL in patients with different causes of CRF receiving domiciliary noninvasive mechanical ventilation [1,15,27,28], and our group has previous experience with COPD patients on NIV [16]. …”

Section: Methodsmentioning

confidence: 99%

Noninvasive Ventilation in Chronic Respiratory Failure: Effects on Quality of Life

et al. 2010

View full text Add to dashboard Cite

Background: Noninvasive ventilation (NIV) has been found to be an essential technique to treat chronic respiratory failure (CRF) resulting from restrictive thoracic disorders (RTD). The last decades were characterized by the expansion of NIV to treat patients suffering from various other conditions, such as chronic obstructive pulmonary disease (COPD) and obesity hypoventilation syndrome (OHS). Objectives: The aim of this study was to evaluate the effect of NIV on health-related quality of life (HRQoL) of patients with CRF during 2 years and to identify parameters associated with changes in HRQoL. Methods: Ninety-one patients with CRF [35 COPD; 17 RTD; 28 OHS; 11 neuromuscular diseases (NMD)] participated. HRQoL was assessed with the SF-36 questionnaire. Additional measurements included blood gases, pulmonary function tests, dyspnea, daytime sleepiness, exacerbations and hospitalizations. The patients were evaluated every 3–6 months. Results: Improvements in SF-36 physical component summary (PCS, p < 0.0001) and mental component summary (MCS, p < 0.0001) scores in RTD and MCS in OHS (p = 0.01) and COPD (p = 0.003) were observed by the third month. PCS in OHS and COPD patients improved by the sixth month (p = 0.003 and p < 0.0001, respectively). NMD patients did not present improvements in HRQoL. Improvements in HRQoL were associated with improvements in PaO₂ and dyspnea in COPD patients, and with total hours of daily ventilator use, improvement in dyspnea, pressure support and expiratory positive airway pressure in RTD patients. Conclusion: Home NIV is consistently effective in improving HRQoL and physiological parameters in patients with CRF. Randomized trials to identify subgroups of COPD responders are justified by our results.

show abstract

Health-related quality of life in patients with chronic respiratory failure after long-term mechanical ventilation

Cited by 44 publications

References 38 publications

Invasive Home Mechanical Ventilation: Living Conditions and Health-Related Quality of Life

Invasive Home Mechanical Ventilation: Living Conditions and Health-Related Quality of Life

The Pulmonary Involvement in Rheumatic Diseases: Pulmonary Effects of Ankylosing Spondylitis and Its Impact on Functionality and Quality of Life

Noninvasive Ventilation in Chronic Respiratory Failure: Effects on Quality of Life

Contact Info

Product

Resources

About