In March 2020, the whole world was impacted by the ripple effects of COVID-19 and was in the midst of battling this infectious disease. A global pandemic caused by a microscopic enemy, which outbroke in Wuhan, China, quickly spread, bringing the world's largest economies to a halt. As a consequence, the financial infrastructures of several countries have been severely damaged. In just 3 weeks, unemployment claims surpassed 16 million in the United States alone, which soared to over 40 million by the end of May 2020. This accounts for a jobless rate of over 24%, a record high in history. Production of chemicals that go into construction and consumer uses trended down in March, and continued plummeting downward in the following months. The chemical manufacturing sector showed a slight drop in employment rate. It is important to understand these broad trends in the demand for chemicals and unemployment in chemistry in the coming months and years. In an economic downturn, fewer people buy new houses and new cars, which decreases the demand for the chemicals that go into manufacturing them. The dramatic drops in the stock market will also affect the pharmaceutical sector. It may become harder for small biotech firms to raise money from investors and seed new positions in start-ups. For major chemical and pharmaceutical companies, if stock prices and quarterly results suffer, we may begin to see layoffs-a reversal of the hiring trends of the past few years. Academia will be affected as well. For many universities and colleges, the sudden disruption in the academic structure of the Spring 2020 semester is having an immediate financial impact. Hiring freezes have begun. However, the effects of the economic downturn on new tenure-track positions won't be clear until early Fall.