Guillain-Barré Syndrome During the Postpartum Period

Introduction Guillain-Barre syndrome (GBS) is an inflammatory poly-radiculoneuropathy occurring usually two weeks after a viral infection.Covid-19 infection represent with respiratory symptoms, but it might manifests with extra pulmonary symptoms, and especially neurological including Guillain-Barre syndrom Case report A 3 years old female patient admitted to the intensive care unit for an acute symmetric and progressive ascending quadriparesis two weeks after an upper respiratory infection, the diagnosis of post covid GBS was maintained, and the evolution was favorable after intraveneous immunoglobulins. Conclusion This case report suggest the probable causal link between COVID 19 and GBS.

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“…This later is an acute peripheral neuropathy manifesting with symmetrical, ascending weakness [ 13 ].…”

Section: Discussionmentioning

confidence: 99%

Guillan barre syndrome in post Covid-19 infection in children

Mezzeoui¹,

Aftiss²,

Aabdi³

et al. 2021

Annals of Medicine &Amp; Surgery

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“…We identified 12 cases of GBS after obstetric procedures (Table 1) [3,[5][6][7][8][9][10][11][12][13][14][15]. Patients' ages ranged from 16 to 34 years old.…”

Section: Literature Review Of Postpartum Gbsmentioning

confidence: 99%

“…Patients' ages ranged from 16 to 34 years old. Six patients were primigravida [8][9][10][11][12]14], four multigravida [3,7,13,15], and two unknowns of gravidity [5,6]. Seven patients underwent C-section [5,7,9,10,[13][14][15], two had vaginal delivery [3,12], one with a forceps-assisted vaginal delivery [8], one opted for pregnancy termination [6], and one report lacked information on the mode of delivery [11].…”

Section: Literature Review Of Postpartum Gbsmentioning

confidence: 99%

“…Six patients were primigravida [8][9][10][11][12]14], four multigravida [3,7,13,15], and two unknowns of gravidity [5,6]. Seven patients underwent C-section [5,7,9,10,[13][14][15], two had vaginal delivery [3,12], one with a forceps-assisted vaginal delivery [8], one opted for pregnancy termination [6], and one report lacked information on the mode of delivery [11]. Among the seven patients who received C-sections, except one who received the surgery electively [13], the other six underwent an urgent or emergent procedure.…”

Section: Literature Review Of Postpartum Gbsmentioning

confidence: 99%

“…However, due to the rarity of postpartum GBS, risk factors, incidence, and prognosis remain unclear. Case reports [3,[5][6][7][8][9][10][11][12][13][14][15] and a singlecenter study [16] suggest that the mode of delivery, preceding infection, and first pregnancy may be associated with the onset of GBS. A retrospective single-center study reported that post-surgical GBS has a worse outcome than non-surgical GBS [17].…”

Section: Introductionmentioning

confidence: 99%

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Postpartum Guillain-Barré Syndrome: A Case Report and Literature Review

Chen,

Norris,

Kwan

et al. 2024

Cureus

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Guillain-Barré syndrome (GBS) is a rare acute-onset neurological disease with significant morbidity and mortality. The risk of GBS increases after delivery. Labor and delivery presents many possible risk factors for GBS. However, risk factors and prognosis of postpartum GBS remain unclear due to its low incidence. Here, we first present a patient with a history of postpartum GBS who returned for an elective repeat cesarean section (C-section). For her previous delivery, the patient received spinal anesthesia for an urgent C-section. She presented postpartum with jaw pain, facial palsy, respiratory difficulty, progressive bilateral lower extremity weakness, and areflexia. The diagnosis of GBS was confirmed by cerebrospinal fluid (CSF) examination, nerve conduction studies (NCS), and electromyography (EMG). Her symptoms of GBS improved after intravenous immunoglobulin (IVIG) treatment. The patient also had an Escherichia colipositive urinary tract infection (UTI), which was treated with nitrofurantoin. For her repeat elective Csection, we performed a dural puncture epidural (DPE) anesthesia. After delivery, she was discharged to home uneventfully. She did not report any new neurological symptoms at her three-week follow-up. Here, we also review published cases of postpartum GBS and discuss peripartum anesthetic considerations for patients with GBS, aiming to inform clinical management of postpartum GBS in the future.

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