Guillain Barre syndrome as a complication of SARS-CoV-2 infection: A case report

Guillain-Barre syndrome is a definite complication of SARS-CoV-2

“…We do not agree with the notion that SARS-CoV-2 “potentially” triggers GBS [ 1 ]. There is meanwhile clear evidence that there is a pathophysiological link between SARS-CoV-2 and GBS from >300 cases reported with SARS-CoV-2 associated GBS as per the end of July 2021 [unpublished results].…”

“…With great interest we read the article by El Aidouni et al about a 49 years old male who developed quadriparesis with sensory disturbances in the lower limbs, and sphincter dysfunction two weeks following a mild COVID-19 infection [ 1 ]. Upon work-up by nerve conduction studies (NCSs), cerebro-spinal fluid (CSF) investigations and cerebral magnetic resonance imaging (MRI), the patient was diagnosed with Guillain-Barre syndrome (GBS) and treated with intravenous immunoglobulines (IVIG), which were ineffective [ 1 ]. The patient did not start to recover before application of plasmapheresis [ 1 ].…”

“…Upon work-up by nerve conduction studies (NCSs), cerebro-spinal fluid (CSF) investigations and cerebral magnetic resonance imaging (MRI), the patient was diagnosed with Guillain-Barre syndrome (GBS) and treated with intravenous immunoglobulines (IVIG), which were ineffective [ 1 ]. The patient did not start to recover before application of plasmapheresis [ 1 ]. The study is appealing but raises the following concerns.…”

“…GBS may exclusively manifest in the cranial nerves (polyneuritis cranialis), only in with dysphagia and weakness of neck and upper limb muscles (PCB) or may manifest in the brainstem as Bickerstaff encephalitis (BBE). There is also the GBS subtype Miller-Fisher syndrome (MFS), which does not follow the definition of GBS provided in the introduction [ 1 ].…”