Guideline adherence and long-term clinical outcomes in patients with acute myocardial infarction: a Japanese Registry of Acute Myocardial Infarction Diagnosed by Universal Definition (J-MINUET) substudy

Wada, Hideki; Ogita, Manabu; Suwa, Satoru; Nakao, Kōichi; Kimura, Kazuo; Ako, Junya; Noguchi, Teruo; Yasuda, Satoshi; Fujimoto, Kazuteru; Nakama, Yasuharu; Morita, Takashi; Shimizu, Wataru; Saito, Yoshihiko; Hirohata, Atsushi; Morita, Yasuhiro; Inoue, Teruo; Okamura, Atsunori; Mano, Toshiaki; Hirata, Kazuhito; Tanabe, Kengo; Shibata, Yoshisato; Owa, Mafumi; Tsujita, Kenichi; Funayama, Hiroshi; Kokubu, Nobuaki; Kozuma, Ken; Uemura, Shiro; Toubaru, Tetsuya; Saku, Keijiro; Nishimura, Kunihiro; Miyamoto, Yoshihiro; Ogawa, Hisao; Ishihara, Masaharu

doi:10.1177/2048872620902024

Cited by 7 publications

(5 citation statements)

References 44 publications

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“…Acute myocardial infarction (AMI), the myocardial ischemic necrosis resulting from the blockage of coronary arteries, is a common critical illness with the characteristics such as rapid disease progression, poor clinical prognosis, and high mortality [ 1 , 2 ]. Early reperfusion is the key to rescuing patients, and studies have found that [ 3 ] the case fatality rate reaches 6% in those who received reperfusion with onset >6 h and decreases to 2% in those who received reperfusion with onset <1 h, indicating that prompt rescue is significant in reducing the mortality of AMI patients [ 4 , 5 ]. Routine first aid processes are cumbersome and significantly delay the rescue time, so optimization is necessary [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

Investigation on the Effect of Graded Emergency Nursing Group under the Assistance of Multidisciplinary First Aid Knowledge Internet-Based Approach on the First Aid of Acute Myocardial Infarction

Song

Han

Rao

et al. 2022

Journal of Healthcare Engineering

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Objective. To analyze the effect of a graded emergency nursing group under the assistance of multidisciplinary first aid knowledge Internet-based approach on the first aid of acute myocardial infarction (AMI). Methods. The clinical data of 90 AMI patients treated in our hospital from March 2019 to March 2020 were selected for the retrospective analysis, and the patients were divided into the observation group and the routine group according to the first aid order, with 45 cases each. The patients in the routine group received the conventional first aid measures, and the graded emergency nursing group mode with the help of multidisciplinary first aid knowledge Internet-based approach was adopted for those in the observation group so as to compare the prognosis, nursing satisfaction scores, etc., between the two groups. Results. Compared with the routine group, patients in the observation group obtained significantly lower various fast reaction indicators and quality of life score ( P < 0.001 ), higher nursing satisfaction score ( P < 0.001 ), lower total complication rate ( P < 0.05 ), higher successful rescue rate ( P < 0.05 ), and lower AMI recurrence rate and PCI reuse rate ( P < 0.05 ). Conclusion. Rescue measures by the graded emergency nursing group with the help of multidisciplinary first aid knowledge Internet-based approach are a reliable method for improving AMI patients, and such strategy greatly promotes patients’ quality of life and reduces the PCI reuse rate. Further research will be conducive to establishing a better solution for AMI patients.

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Section: Introductionmentioning

confidence: 99%

Investigation on the Effect of Graded Emergency Nursing Group under the Assistance of Multidisciplinary First Aid Knowledge Internet-Based Approach on the First Aid of Acute Myocardial Infarction

Song

Han

Rao

et al. 2022

Journal of Healthcare Engineering

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“…More importantly, the encouraging findings of the absence of a July effect reflect greater adherence to guideline-directed clinical care and protocols and an overall decline in in-hospital mortality associated with AMI in the contemporary era. [27][28][29][30] Further, the increased focus on improving quality of cardiovascular care has resulted in several individual and composite quality measures and metrics that are frequently assessed through national programs. [31][32][33] Therefore, in recent years a greater emphasis has been placed on care-patterns and outcomes of acute cardiac conditions including AMI.…”

Section: Discussionmentioning

confidence: 99%

“…These contrasting findings could be related to the larger and more recent study cohort in the present analysis and differences in classification of hospitals as teaching intensive and nonteaching. More importantly, the encouraging findings of the absence of a July effect reflect greater adherence to guideline‐directed clinical care and protocols and an overall decline in in‐hospital mortality associated with AMI in the contemporary era 27–30 . Further, the increased focus on improving quality of cardiovascular care has resulted in several individual and composite quality measures and metrics that are frequently assessed through national programs 31–33 .…”

Section: Discussionmentioning

confidence: 99%

No “July Effect” in the management and outcomes of acute myocardial infarction: An 18‐year United States national study

Patlolla

Truesdell²,

Basir

et al. 2023

Cathet Cardio Intervent

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Background There has been conflicting reports on the effect of new trainees on clinical outcomes at teaching hospitals in the first training month (July in the United States of America). We sought to assess this “July effect” in a contemporary acute myocardial infarction (AMI) population. Methods Adult (>18 years) AMI hospitalizations in May and July in urban teaching and urban nonteaching hospitals in the United States were identified from the HCUP‐NIS database (2000–2017). In‐hospital mortality was compared between May and July admissions. A difference‐in‐difference analysis comparing a change in outcome from May to July in teaching hospitals to a change in outcome from May to July in nonteaching hospitals was also performed. Results A total of 1,312,006 AMI hospitalizations from urban teaching (n = 710,593; 54.2%) or nonteaching (n = 601,413; 45.8%) hospitals in the months of May and July were evaluated. May admissions in teaching hospitals, had greater comorbidity, higher rates of acute multiorgan failure (10.6% vs. 10.2%, p < 0.001) and lower rates of cardiac arrest when compared to July admissions. July AMI admissions had lower in‐hospital mortality compared to May (5.6% vs. 5.8%; adjusted odds ratio 0.94 [95% confidence interval 0.92–0.97]; p < 0.001) in teaching hospitals. Using the difference‐in‐difference model, there was no evidence of a July effect for in‐hospital mortality (p = 0.19). Conclusions There was no July effect for in‐hospital mortality in this contemporary AMI population.

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“…The results were derived from the clinical practice in Korea and may not fit in the other regions. 9 , 36 …”

Section: Discussionmentioning

confidence: 99%

Adherence to guideline-directed medical therapy and 3-year clinical outcome following acute myocardial infarction

Lee

Hyun

Choi

et al. 2023

European Heart Journal Open

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Aims Despite the well-established clinical benefits and strong recommendations in clinical guidelines, adherence to guideline-directed medical therapy (GDMT) is known to be insufficient. We investigated the adherence to GDMT and its impact on the 3-year clinical outcomes in patients with acute myocardial infarction (AMI). Methods and results Source data were obtained from KAMIR-NIH, a Korean multicenter observational registry. GDMT was defined according to the ACC/AHA class I recommendations. Adherence to GDMT was assessed at discharge and every year thereafter. The differences in clinical characteristics between patients receiving and those not receiving GDMT were adjusted using propensity score matching (PSM) or inverse probability of treatment weighting (IPTW). The primary endpoint was major adverse cardiovascular events (MACE), which was a composite of all-cause death and non-fatal MACE, including MI, revascularization, or stroke. Of 12,815 patients, GDMT adherence was 70.2% at discharge, and decreased gradually into 54.6% at 3-year. GDMT at discharge was associated with lower MACE risk in the unadjusted analysis (HR=0.51, 95%CI=0.47–0.55, p<0.001) and also in the PSM- or IPTW-adjusted analyses (HR=0.77, 95%CI=0.69–0.86; HR=0.79, 95%CI=0.72–0.86; p<0.001, all). These findings were replicated in the 1-year or 2-year landmark analyses (HR=0.58 to 0.82, p<0.01, all). Conclusion Adherence to GDMT was suboptimal among patients with AMI in Korea. As the adherence to GDMT was associated with a lower incidence of MACE during 3-year follow-up, the maintenance of long-term GDMT might be crucial for patients with AMI.

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Guideline adherence and long-term clinical outcomes in patients with acute myocardial infarction: a Japanese Registry of Acute Myocardial Infarction Diagnosed by Universal Definition (J-MINUET) substudy

Cited by 7 publications

References 44 publications

Investigation on the Effect of Graded Emergency Nursing Group under the Assistance of Multidisciplinary First Aid Knowledge Internet-Based Approach on the First Aid of Acute Myocardial Infarction

Investigation on the Effect of Graded Emergency Nursing Group under the Assistance of Multidisciplinary First Aid Knowledge Internet-Based Approach on the First Aid of Acute Myocardial Infarction

No “July Effect” in the management and outcomes of acute myocardial infarction: An 18‐year United States national study

Adherence to guideline-directed medical therapy and 3-year clinical outcome following acute myocardial infarction

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