Consequently, elderly patients are less likely to receive GDMT than younger patients. 5 Japan, a rapidly aging society, has a large number of elderly patients with coronary artery disease. 6-8,10 Comprehensive information from Japan will be beneficial for developing perspectives on the use of GDMT in other countries.Therefore, in the present study we investigated the impact of GDMT, which is a combination of aspirin or a P2Y12 inhibitor, angiotensin-converting enzyme inhibitor (ACEi) or angiotensin receptor blocker (ARB), β-blocker, and statin, at discharge on long-term mortality in patients with AMI aged ≥80 years who underwent emergency PCI.
Guideline-directed medical therapy (GDMT) for secondary prevention improves clinical outcomes in patients with acute myocardial infarction (AMI). 1-4 With an aging population, percutaneous coronary intervention (PCI) is being performed more often even in elderly patients with AMI, 5-8 and subsequent management of these patients has received increased attention. However, the effect of GDMT at discharge on mortality in elderly patients with AMI who undergo emergency PCI remains unclear because cardiovascular trials rarely include elderly patients, and guidelines are often based on the extrapolation of data from a substantially younger population. 5,9