The present study was designed to study the effect of single cell protein (SCP) on growth performances in broiler chicken. Day old chicks (600) were distributed in six groups and each group was consisting of four replicates with 25 birds in each. Soybean meal was replaced by SCP at the level of 0 (control), 2% (T1), 4% (T2), 6% (T3), 8% (T4) and 10% (T5). Total duration of the trial was 42 days. There was decrease in body weight, feed intake, performance index and increase in FCR with higher inclusion level but at the 2% level, the results were comparable with control. Dressing%, breast yield% and abdominal fat% decreased as the replacement of the soybean meal increased. However, hot carcass weight%, neck%, wing%, drumstick%, thigh%, back% showed no difference. Hemoglobin, total protein, albumin, globulin, glucose, ALT and AST level decreased significantly as the inclusion level increases but the level of uric acid increased. It can be concluded that SCP with 2% replacement of the soybean meal can be included in the commercial broiler ration without any adverse effect.