Green synthesis, characterization and anti-inflammatory activity of silver nanoparticles using European black elderberry fruits extract

David, Luminiţa; Moldovan, Bianca; Vulcu, Adriana; Olenic, Liliana; Perde-Schrepler, Maria; Fischer‐Fodor, Eva; Florea, Adrian; Crışan, Maria; Chiorean, Ioana; Clichici, Simona; Filip, Gabriela Adriana

doi:10.1016/j.colsurfb.2014.08.018

Cited by 192 publications

(105 citation statements)

References 43 publications

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“…In previous studies, the maximum percentage of edema inhibition was exhibited by Ag-NPs at 50 mg/kg body weight. 58,97 Other ferns, including Equisetum arvense, Cyathea phalerata, and Blechnum occidentale, have also been shown to display anti-inflammatory and antioxidant activity due to the presence of secondary metabolites like phenolic compounds. 98,99 Over the duration of this study, no deaths occurred in any of the experimental groups.…”

mentioning

confidence: 99%

Biosynthesis, characterization, and evaluation of bioactivities of leaf extract-mediated biocompatible silver nanoparticles from an early tracheophyte, Pteris tripartita Sw.

Baskaran

Vigila

Thangaraj

et al. 2016

IJN

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mentioning

confidence: 99%

Biosynthesis, characterization, and evaluation of bioactivities of leaf extract-mediated biocompatible silver nanoparticles from an early tracheophyte, Pteris tripartita Sw.

Baskaran

Vigila

Thangaraj

et al. 2016

IJN

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“…Besides the well-known compounds (vitamins C, E, beta-carotene etc), phenolics with documented antioxidative properties gained great interest being added to diet or used for topical applications (Lorencini M et al, 2014;Robbins, 2003). Biomaterials based on nanoparticles and natural extracts were tested recently as antiinflammatory agents, beneficial in treating skin diseases (David et al, 2014;Wu et al, 2015).…”

Section: Morphology Analysismentioning

confidence: 99%

Modulation of the UV-B-induced Oxidative Stress and Apoptosis in HaCaT Cell Line with Calluna vulgaris Extract

Virág

Brie

Burz

et al. 2015

Not Bot Hort Agrobot Cluj

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The reactive oxygen species (ROS) production due to ultraviolet B (UV-B) exposure is extremely harmful to the skin. It causes lesions of DNA, proteins and lipids and leads to cellular death. In the present study the UV-B-induced ROS and subsequent apoptosis in the human keratinocyte cell line (HaCaT) were counterbalanced by a plant extract with antioxidant capacity. Some molecules modulated by common heather (Calluna vulgaris) (CV) extract through which this may exert its photoprotective effects were also identified. The ROS were evaluated with CM-H2DCFDA assay, while apoptosis and Bax-α/Bcl-xL molecules with ELISA. The extract was standardized according to its polyphenolic content and the most important biologically active compounds, such as hyperozid, quercetin, isoquercetin, kampferol were evidenced by high-performance liquid chromatography. The UV-B induced ROS production occurred at its highest level at 2 h after the exposure of the HaCaT cells, while apoptosis later, at 4 h. The most significant changes in Bax-α and Bcl-XL proteins induced by UV-B, as well as the highest effect of the extract on apoptosis, were both registered at 4 h. The CV extract decreased concentration-and time-dependently the UV-B-induced ROS production and prevented apoptosis. These effects of CV occurred, at least to a certain extent, due to the modulation of Bax-α/Bcl-XL proteins. These findings suggest that skin cells could be protected from some of the UV-B-induced harmful effects by the administration of the CV extract, which may be further exploited as a potential photoprotective agent.

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“…Each area was examined in greyscale mode in order to identify the morphological and structural parameters, with Doppler techniques and elastography. Part of our work concerning the role of ultrasound in the assessment of the therapeutic eicacy in plaque psoriasis patients was already published [16,17,21]. Therefore, in this study, we focused on the examination of the nail apparatus.…”

Section: Methodsmentioning

confidence: 99%

“…The local changes of the tissue elasticity corresponding to a psoriasis plaque are revealed in Related to the therapeutic approach in psoriasis patients, our group used high-frequency ultrasound to investigate the skin reaction after topical therapy with low potency steroids (cortisone) and natural extracts of cranberry and black elderberry, showing that ultrasound can evaluate with great accuracy the changes in psoriasis plaques induced by various topical therapies [16,17]. We assessed in a comparative manner the anti-inlammatory efect of the natural extracts of cranberry and black elderberry and of cortisone with control lesions only treated with emollients.…”

Section: An Interdisciplinary Approach To Psoriasismentioning

confidence: 99%

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Ultrasonography as a New, Non-Invasive Imagistic Technique Used for the Diagnosis and Monitoring of Psoriasis

Crışan¹,

Badea²,

Crişan³

et al. 2017

An Interdisciplinary Approach to Psoriasis

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Psoriasis is a chronic inlammatory autoimmune disease that involves the skin, nails, joints and other organs, being a systemic disease. Regardless of the clinical form, sonography can be efectively used to complete the clinical diagnosis. Aim:The identiication of non-invasive sonographic markers for the assessment of the severity of the disease and the eicacy of various therapies. Our study involved two research directions: (a) clinical and imagistic assessment of the skin and nail psoriasis lesions and (b) the imagistic evaluation of the therapeutic eicacy in psoriasis plaques and nail psoriasis by acquirement of sonographic images prior and after various therapies. Methods:In our prospective study, we used a multimodal evaluation of the disease, based on a non-invasive approach: clinical exam, dermoscopy, conventional and high frequency sonography, Doppler, power Doppler and elastography. Conclusions:Ultrasonography is an important tool for the non-invasive assessment of psoriatic lesions. It ofers speciic markers related to morphology, elasticity and blood supply of the lesions, improving the diagnosis and monitoring of the skin and nail lesions.

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Green synthesis, characterization and anti-inflammatory activity of silver nanoparticles using European black elderberry fruits extract

Cited by 192 publications

References 43 publications

Biosynthesis, characterization, and evaluation of bioactivities of leaf extract-mediated biocompatible silver nanoparticles from an early tracheophyte,<em> Pteris tripartita</em> Sw.

Biosynthesis, characterization, and evaluation of bioactivities of leaf extract-mediated biocompatible silver nanoparticles from an early tracheophyte,<em> Pteris tripartita</em> Sw.

Modulation of the UV-B-induced Oxidative Stress and Apoptosis in HaCaT Cell Line with <i>Calluna vulgaris</i> Extract

Ultrasonography as a New, Non-Invasive Imagistic Technique Used for the Diagnosis and Monitoring of Psoriasis

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