2020
DOI: 10.1007/s10311-020-00984-0
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Green synthesis, biomedical and biotechnological applications of carbon and graphene quantum dots. A review

Abstract: Carbon and graphene quantum dots are prepared using top-down and bottom-up methods. Sustainable synthesis of quantum dots has several advantages such as the use of low-cost and non-toxic raw materials, simple operations, expeditious reactions, renewable resources and straightforward post-processing steps. These nanomaterials are promising for clinical and biomedical sciences, especially in bioimaging, diagnosis, bioanalytical assays and biosensors. Here we review green methods for the fabrication of quantum do… Show more

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Cited by 318 publications
(164 citation statements)
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“…Oxygen-containing functional groups are responsible for good solubility in polar solvents such as water or ethanol [7,8] in the concentration of 5 mg mL −1 [9] or even higher, > 15 mg mL −1 [10]. Properties that distinguish GQDs from other carbon nanomaterials such as carbon nanotubes and graphene, are high dispersibility in water and polar organic solvents, photoluminescence [11], good biocompatibility [12].…”
Section: Introductionmentioning
confidence: 99%
“…Oxygen-containing functional groups are responsible for good solubility in polar solvents such as water or ethanol [7,8] in the concentration of 5 mg mL −1 [9] or even higher, > 15 mg mL −1 [10]. Properties that distinguish GQDs from other carbon nanomaterials such as carbon nanotubes and graphene, are high dispersibility in water and polar organic solvents, photoluminescence [11], good biocompatibility [12].…”
Section: Introductionmentioning
confidence: 99%
“…Generally, biologically-derived chemicals or natural product extracts obtained from bio-renewable sources with their promising reducing, stabilizing and capping potentials can be deployed for the greener production of mono- and multi-metallic NPs ( Figure 3 ) [ 6 , 79 , 80 , 81 , 82 , 83 ]. However, there are still some important challenging issues persist, including the exact mechanisms for NP formation, limitations to scale up and the reproducibility of procedures [ 52 ].…”
Section: Greener and Sustainable Synthesis Of Trimetallic Npsmentioning
confidence: 99%
“…Carbon dots have been extensively reviewed in term of synthesis, physicochemical properties, as well as their potential applications. Here, we refer the reader to the numerous good reviews on carbon dots [72,[82][83][84][85][86][87][88].…”
Section: Carbon Dots As Nanothermometersmentioning
confidence: 99%