Green Synthesis and Characterization of Halloysite Nanoclay/Curcumin/Ag Hybrid Nano Materials for Antibacterial Applications

Sudhakar, K.; Moloi, S.J.; Rao, K. Madhusudhana

doi:10.1007/s10904-017-0600-2

Cited by 18 publications

(7 citation statements)

References 34 publications

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“…These results reflect that curcumin oxide not only acts as a strong reducing agent for Ag + but also has extra stabilizing action on silver nanoparticles formed within the matrix of chitosan/Ag-curcumin nanocomposite hydrogel [34]. Moreover, the spherical shape of silver nanoparticles may be due to the presence of phenolic hydroxyl groups in curcumin during hydrogel formation [35].…”

Section: Tem Analysismentioning

confidence: 79%

Antibacterial Properties and pH Sensitive Swelling of Insitu Formed Silver-Curcumin Nanocomposite Based Chitosan Hydrogel

El‐Hady

Saeed

2020

Polymers

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A simple method was used to prepare curcumin/silver nanocomposite based chitosan hydrogel. In an alkaline medium, chitosan and chitosan nanocomposite hydrogels were prepared using the physical crosslinking method. The prepared hydrogels were stable for a long period at room temperature. In one step, silver nanoparticles were prepared insitu using silver nitrate solution and curcumin oxide within the hydrogel network formation. In the meantime, curcumin compound served as both a reducing and stabilizing agent. The structure and surface morphology of nanocomposite hydrogels were characterized by FTIR, SEM, and EDX analysis confirmed the formation of silver nanoparticles within the hydrogel network. Moreover, Images of TEM showed a spherical shape of silver nanoparticles with an average size of 2–10 nm within the matrix of the hydrogel. The formation mechanism of nanocomposite based hydrogel was reported. Besides that, the effect of chitosan and silver nitrate concentrations were studied. The swelling capacity of the prepared nanocomposite hydrogels was also performed at different pH of 4, 7, and 9. From the experimental results, the swelling capacity of hydrogels depends on the concentrations of chitosan and silver nitrate. The prepared composite based hydrogel exceeds a higher swelling degree than chitosan hydrogels at low pH. The antibacterial activity of the nanocomposite hydrogels was also examined; the results showed that the prepared nanocomposite hydrogels outperformed the pure chitosan hydrogels. This shows them to be a promising material for the biomedical field as a wound dressing and drug release.

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Section: Tem Analysismentioning

confidence: 79%

Antibacterial Properties and pH Sensitive Swelling of Insitu Formed Silver-Curcumin Nanocomposite Based Chitosan Hydrogel

El‐Hady

Saeed

2020

Polymers

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“… 193 , 194 The composite nanofilms based on curcumin, chitosan, and silver nanoparticles or nanoclay have been reported to induce synergistic antibacterial effects. 195 , 196 …”

Section: Nanotheranostics Perspectivementioning

confidence: 99%

“…193,194 The composite nanofilms based on curcumin, chitosan, and silver nanoparticles or nanoclay have been reported to induce synergistic antibacterial effects. 195,196 Niclosamide is an FDA-approved antihelmintic drug developed for the treatment of tapeworms and nematodes. Currently, WHO has listed it as one of the essential drugs.…”

Section: Nanotheranostics Perspectivementioning

confidence: 99%

“…It reflects the superior anti-pathogenic activity of curcumin when encapsulated in nanoparticles. The PEGylated lipid formulations of curcumin have been found to be 10-fold more effective for malaria than crude curcumin. , The composite nanofilms based on curcumin, chitosan, and silver nanoparticles or nanoclay have been reported to induce synergistic antibacterial effects. , …”

Section: Nanotheranostics Perspectivementioning

confidence: 99%

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Comprehensive Review on Current Interventions, Diagnostics, and Nanotechnology Perspectives against SARS-CoV-2

et al. 2020

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The coronavirus disease 2019 (COVID-19) has dramatically challenged the healthcare system of almost all countries. The authorities are struggling to minimize the mortality along with ameliorating the economic downturn. Unfortunately, until now, there has been no promising medicine or vaccine available. Herein, we deliver perspectives of nanotechnology for increasing the specificity and sensitivity of current interventional platforms toward the urgent need of quickly deployable solutions. This review summarizes the recent involvement of nanotechnology from the development of a biosensor to fabrication of a multifunctional nanohybrid system for respiratory and deadly viruses, along with the recent interventions and current understanding about severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

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“…Encasing silver inside the nanotubes allowed the prevention of colour changes in Ag-halloysite doped white paint, while the direct addition of silver nanoparticles converted the coating to a yellow-grey color. In [79], the dispersion of halloysite in a silver salt solution was kept in a vacuum for five cycles, followed by reduction with curcumin. Curcumin is not only a reducing agent, but it also possesses antibacterial activity against gram-positive and gram-negative bacteria.…”

Section: Clay Nanotubes Loading With Antimicrobial Agentsmentioning

confidence: 99%

Antimicrobial Applications of Clay Nanotube-Based Composites

et al. 2019

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Halloysite nanotubes with different outer surface/inner lumen chemistry (SiO2/Al2O3) are natural objects with a 50 nm diameter hollow cylindrical structure, which are able to carry functional compounds both inside and outside. They are promising for biological applications where their drug loading capacity combined with a low toxicity ensures the safe interaction of these nanomaterials with living cells. In this paper, the antimicrobial properties of the clay nanotube-based composites are reviewed, including applications in microbe-resistant biocidal textile, paints, filters, and medical formulations (wound dressings, drug delivery systems, antiseptic sprays, and tissue engineering scaffolds). Though halloysite-based antimicrobial materials have been widely investigated, their application in medicine needs clinical studies. This review suggests the scalable antimicrobial nano/micro composites based on natural tubule clays and outlines research and development perspectives in the field.

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Green Synthesis and Characterization of Halloysite Nanoclay/Curcumin/Ag Hybrid Nano Materials for Antibacterial Applications

Cited by 18 publications

References 34 publications

Antibacterial Properties and pH Sensitive Swelling of Insitu Formed Silver-Curcumin Nanocomposite Based Chitosan Hydrogel

Antibacterial Properties and pH Sensitive Swelling of Insitu Formed Silver-Curcumin Nanocomposite Based Chitosan Hydrogel

Comprehensive Review on Current Interventions, Diagnostics, and Nanotechnology Perspectives against SARS-CoV-2

Antimicrobial Applications of Clay Nanotube-Based Composites

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