Green approaches in sample preparation of bioanalytical samples prior to chromatographic analysis

Filippou, Olga; Bitas, Dimitrios; Samanidou, Victoria

doi:10.1016/j.jchromb.2016.08.040

Cited by 119 publications

(76 citation statements)

References 114 publications

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“…Because of the unique properties of ILs, they have played an important role in sample preparation technique. [27][28][29] And more researchers pay attention to the modication of IL and their usage in the pesticides residue analysis.…”

mentioning

confidence: 99%

Freezing temperature controlled deep eutectic solvent dispersive liquid–liquid microextraction based on solidification of floating organic droplets for rapid determination of benzoylureas residual in water samples with assistance of metallic salt

Yang

Hong

et al. 2017

RSC Adv.

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mentioning

confidence: 99%

Freezing temperature controlled deep eutectic solvent dispersive liquid–liquid microextraction based on solidification of floating organic droplets for rapid determination of benzoylureas residual in water samples with assistance of metallic salt

Yang

Hong

et al. 2017

RSC Adv.

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“…This approach was checked in several theoretical studies (David, Galaon, & Aboul-Enein, 2014;Udrescu, Medvedovici, & David, 2008), and successfully applied for bioequivalence studies for some drugs (Medvedovici, Udrescu, Albu, Tache, & David, 2011;Udrescu et al, 2011). The procedure becomes safer for the technical personal involved in sample preparation when the organic solvent is environmentally friendly, although all organic solvents have adverse effects on the environment (Filippou, Bitas, & Samanidou, 2017), or more pleasant (limonene) when manipulated for SP (Medvedovici, Udrescu, & David, 2013). Schematic approaches of LLE processes applied to the isolation of analyte(s) from a biological fluid matrix biomatrix is removed before LLE for improving the selectivity of SP.…”

Section: Liquid-liquid Extractionmentioning

confidence: 99%

Sample preparation for large‐scale bioanalytical studies based on liquid chromatographic techniques

Medvedovici

Bacalum

David

2017

Biomedical Chromatography

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Quality of the analytical data obtained for large-scale and long term bioanalytical studies based on liquid chromatography depends on a number of experimental factors including the choice of sample preparation method. This review discusses this tedious part of bioanalytical studies, applied to large-scale samples and using liquid chromatography coupled with different detector types as core analytical technique. The main sample preparation methods included in this paper are protein precipitation, liquid-liquid extraction, solid-phase extraction, derivatization and their versions. They are discussed by analytical performances, fields of applications, advantages and disadvantages. The cited literature covers mainly the analytical achievements during the last decade, although several previous papers became more valuable in time and they are included in this review.

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“…Solid-phase extraction (SPE) and liquid-liquid extraction (LLE) are two widely used and well-established techniques for the extraction of organic compounds. However, these conventional techniques tend to have many fundamental drawbacks such as complicated and time-consuming steps, requirement for a large amount of organic solvents and sample, as well as difficulties in automation [1][2][3][4]. Recent trends in sample preparation are focused on the progressive replacement of those techniques by miniaturized and environment-friendly techniques, such as solid-phase microextraction (SPME) [5], dispersive liquid-liquid microextraction (DLLME) [6], fabric phase sorptive extraction (FPSE) [7] and dispersive solid-phase extraction (d-SPE) [8].…”

Section: Introductionmentioning

confidence: 99%

Magnetic Solid-Phase Extraction of Organic Compounds Based on Graphene Oxide Nanocomposites

et al. 2020

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Graphene oxide (GO) is a chemical compound with a form similar to graphene that consists of one-atom-thick two-dimensional layers of sp2-bonded carbon. Graphene oxide exhibits high hydrophilicity and dispersibility. Thus, it is difficult to be separated from aqueous solutions. Therefore, functionalization with magnetic nanoparticles is performed in order to prepare a magnetic GO nanocomposite that combines the sufficient adsorption capacity of graphene oxide and the convenience of magnetic separation. Moreover, the magnetic material can be further functionalized with different groups to prevent aggregation and extends its potential application. Until today, a plethora of magnetic GO hybrid materials have been synthesized and successfully employed for the magnetic solid-phase extraction of organic compounds from environmental, agricultural, biological, and food samples. The developed GO nanocomposites exhibit satisfactory stability in aqueous solutions, as well as sufficient surface area. Thus, they are considered as an alternative to conventional sorbents by enriching the analytical toolbox for the analysis of trace organic compounds.

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Green approaches in sample preparation of bioanalytical samples prior to chromatographic analysis

Cited by 119 publications

References 114 publications

Freezing temperature controlled deep eutectic solvent dispersive liquid–liquid microextraction based on solidification of floating organic droplets for rapid determination of benzoylureas residual in water samples with assistance of metallic salt

Freezing temperature controlled deep eutectic solvent dispersive liquid–liquid microextraction based on solidification of floating organic droplets for rapid determination of benzoylureas residual in water samples with assistance of metallic salt

Sample preparation for large‐scale bioanalytical studies based on liquid chromatographic techniques

Magnetic Solid-Phase Extraction of Organic Compounds Based on Graphene Oxide Nanocomposites

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