Gravity of aortic arch calcification in adult patients

Symeonidis, G.; Papanas, N.; Giannakis, I.; Mavridis, G.; Lakasas, G.; Kyriakidis, G.; Artopoulos, I.

doi:10.1016/s1567-5688(01)80452-9

Cited by 25 publications

(36 citation statements)

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“…It is possible to detect Arch calcification by chest X-ray examination, [1][2][3][4][5] calcification of the Asc and Des is often not detected because of cardiac and mediastinal shadows. CT scanning does not have this drawback and thus allows easier and more precise diagnosis of aortic calcification and morphological abnormalities.…”

Section: Discussionmentioning

confidence: 99%

“…[1][2][3][4][5] The development of computed tomography (CT) has enabled the non-invasive imaging of the cardiovascular system and calcification of the coronary arteries (CAC) and aorta can now be detected more reliably. Previous studies have revealed a strong relationship between coronary artery disease (CAD) and CAC detected by CT. [6][7][8][9][10][11][12][13] The recent progression to multislice spiral CT and electronbeam CT (EBCT) has enabled noninvasive detection of significant coronary stenosis and occlusions 14,15 and in a study of subjects who underwent EBCT examination for evaluation of CAC, the prevalence of aortic calcification was 23%.…”

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confidence: 99%

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Aortic Calcification Detected in a Mass Chest Screening Program Using a Mobile Helical Computed Tomography Unit-Relationship to Risk Factors and Coronary Artery Disease-

Itani

Watanabe

Masuda

2004

Circ J

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

Aortic Calcification Detected in a Mass Chest Screening Program Using a Mobile Helical Computed Tomography Unit-Relationship to Risk Factors and Coronary Artery Disease-

Itani

Watanabe

Masuda

2004

Circ J

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“…As shown in Fig. 1, AAC extent was divided into four grades according to the categorization proposed in a previous report 17) . Briefly, we scored the area of calcification as four grades: grade 0, no visible calcification; grade 1, small spots of calcification or a single thin area of calcification of the aortic knob; grade 2, one or more areas of thick calcification; grade 3, circular calcification of the aortic knob.…”

Section: Assessment Of Aortic Arch Calcificationmentioning

confidence: 99%

Validity and Usefulness of Aortic Arch Calcification in Chest X-Ray

Hashimoto

Iijima

Hashimoto

et al. 2009

J Atheroscler Thromb

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Background: Arterial calcification is associated with cardiovascular (CV) disease, to be leading to vessel wall stiffness and causing the management of hemodynamics in the elderly more difficult. Here, we compared the extent of calcification in the aortic arch by reviewing chest X-rays to that in the abdominal aorta as assessed by more detailed examinations. In addition, the validity of the grading and the relationship of this useful grading to clinical risk factors were evaluated. Methods and Results:The extent of aortic arch calcification (AAC) on a postero-anterior plain chest X-ray was divided into four grades (0 to 3). First, AAC grade was assessed in patients who underwent two quantitative examinations for abdominal aortic calcification; lateral radiograph of lumbar spine and/or computer tomography, and was positively correlated with the abdominal aortic calcification level. Subsequently, AAC grade in 239 out-patients (115 men; mean age, 61.9 years) was also evaluated, and was 0, 1, 2, and 3 in 46%, 22%, 29%, and 4% of the population, respectively, was significantly associated with pulse pressure and intima-media thickness. AAC grade in patients with diabetes or renal dysfunction was significantly higher than in those without each risk, but there was no association with other risk factors. In addition, AAC grade was positively correlated with risk factor clustering. Conclusion: Assessment of AAC detectable on a chest X-ray is very useful and its grade reflects the magnitude of calcified change in the whole aorta. In addition, AAC evaluation may provide supportive information for atherosclerotic risk stratification.

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“…The KDIGO clinical practice guideline recommends plain X-ray films of the lumbar spine for the detection and assessment of cardiovascular calcification in HD patients [21]. The AoAC identified in plain chest X-ray is associated with an increased risk of coronary artery disease and is linked to cardiovascular risk factors such as age, hypertension, dyslipidemia and diabetes mellitus in the general population [22,23]. Moreover, compared with traditional risk factors, AoAC is an independent determinant of cardiovascular outcome [24].…”

Section: Discussionmentioning

confidence: 99%

Association Between Risk Factors Including Bone-Derived Biomarkers and Aortic Arch Calcification in Maintenance Hemodialysis Patients

Nitta

Hanafusa

Okazaki

et al. 2018

Kidney Blood Press Res

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Background/Aims: Aortic arch calcification (AoAC) is frequently detected in maintenance hemodialysis (MHD) patients and is associated with cardiovascular and all-cause mortality. We investigated the factors associated with AoAC and analyzed the relationship between the factors including bone-derived biomarkers and AoAC. Methods: We enrolled 389 stable MHD patients. AoAC was assessed using chest-X ray examination. Demographic data was collected in addition to serum levels of biochemical and bone-derived biomarkers, including sclerostin and fibroblast growth factor-23 (FGF-23). Results: Two hundred sixteen patients (55.5%) had AoAC. Patients with AoAC score ≥ 4 were older, with a higher percentage being male, and exhibited lower serum levels of albumin and triglyceride. Serum FGF-23 levels were inversely associated with AoAC severity, and FGF-23was directly related to vascular calcification. Age, gender, and dialysis vintage were independent predictors of AoAC. Conclusion: MHD patients have a high prevalence of AoAC. The grade of AoAC was dependent on older age in association with longer dialysis vintage. Levels of circulating FGF-23 but not sclerostin were related to AoAC severity. Serum FGF-23 levels were independently associated with AoAC.

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Gravity of aortic arch calcification in adult patients

Cited by 25 publications

References 0 publications

Aortic Calcification Detected in a Mass Chest Screening Program Using a Mobile Helical Computed Tomography Unit-Relationship to Risk Factors and Coronary Artery Disease-

Aortic Calcification Detected in a Mass Chest Screening Program Using a Mobile Helical Computed Tomography Unit-Relationship to Risk Factors and Coronary Artery Disease-

Validity and Usefulness of Aortic Arch Calcification in Chest X-Ray

Association Between Risk Factors Including Bone-Derived Biomarkers and Aortic Arch Calcification in Maintenance Hemodialysis Patients

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