Graphene-Based Sensors for Human Health Monitoring

Huang, Haizhou; Shi, Shaobo; Wu, N. J.; Wan, Hao; Wan, Songming; Bi, Hengchang; Sun, Litao

doi:10.3389/fchem.2019.00399

Cited by 238 publications

(160 citation statements)

References 188 publications

Supporting

Mentioning

156

Contrasting

Order By: Relevance

“…These data can be then applied to design and tune the specific catalytic activity of GO-based nanomaterials for sensing and environmental applications [21][22][23]. In addition, over the last decade, heteroatom-doped GO materials have been extensively studied to tune the structural and electronic properties of GO for applications in energy storage and catalytic sensing [24][25][26][27].The purpose of this study was three-fold: (i) to develop an advanced electrochemical sensor for the detection of naproxen; (ii) to compare the performance of various GO-based sensors and rationalize the effects of oxygenated functional groups; and (iii) to investigate the effects of dopants on the performance of the GO-based electrochemical sensors.…”

mentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Graphene-Oxide-Based Electrochemical Sensors for the Sensitive Detection of Pharmaceutical Drug Naproxen

Qian

Thiruppathi

Elmahdy

et al. 2020

Sensors

View full text Add to dashboard Cite

Here we report on a selective and sensitive graphene-oxide-based electrochemical sensor for the detection of naproxen. The effects of doping and oxygen content of various graphene oxide (GO)-based nanomaterials on their respective electrochemical behaviors were investigated and rationalized. The synthesized GO and GO-based nanomaterials were characterized using a field-emission scanning electron microscope, while the associated amounts of the dopant heteroatoms and oxygen were quantified using x-ray photoelectron spectroscopy. The electrochemical behaviors of the GO, fluorine-doped graphene oxide (F-GO), boron-doped partially reduced graphene oxide (B-rGO), nitrogen-doped partially reduced graphene oxide (N-rGO), and thermally reduced graphene oxide (TrGO) were studied and compared via cyclic voltammetry (CV) and differential pulse voltammetry (DPV). It was found that GO exhibited the highest signal for the electrochemical detection of naproxen when compared with the other GO-based nanomaterials explored in the present study. This was primarily due to the presence of the additional oxygen content in the GO, which facilitated the catalytic oxidation of naproxen. The GO-based electrochemical sensor exhibited a wide linear range (10 µM–1 mM), a high sensitivity (0.60 µAµM−1cm−2), high selectivity and a strong anti-interference capacity over potential interfering species that may exist in a biological system for the detection of naproxen. In addition, the proposed GO-based electrochemical sensor was tested using actual pharmaceutical naproxen tablets without pretreatments, further demonstrating excellent sensitivity and selectivity. Moreover, this study provided insights into the participatory catalytic roles of the oxygen functional groups of the GO-based nanomaterials toward the electrochemical oxidation and sensing of naproxen.

show abstract

mentioning

confidence: 99%

mentioning

confidence: 99%

Graphene-Oxide-Based Electrochemical Sensors for the Sensitive Detection of Pharmaceutical Drug Naproxen

Qian

Thiruppathi

Elmahdy

et al. 2020

Sensors

View full text Add to dashboard Cite

show abstract

“…In all cases it was observed an improvement of the polymer mechanical properties. Graphene based nanocomposites were successfully implemented in electrochemical applications [368,369], supercapacitors [370,371], lithium ion batteries [372,373], solar cell [374,375], sensors [376,377], drug delivery and tissue engineering [378][379][380], water purification [381,382].…”

Section: Graphene Oxidementioning

confidence: 99%

The Role of Functionalization in the Applications of Carbon Materials: An Overview

Speranza

2019

View full text Add to dashboard Cite

The carbon-based materials (CbMs) refer to a class of substances in which the carbon atoms can assume different hybridization states (sp 1 , sp 2 , sp 3 ) leading to different allotropic structures -. In these substances, the carbon atoms can form robust covalent bonds with other carbon atoms or with a vast class of metallic and non-metallic elements, giving rise to an enormous number of compounds from small molecules to long chains to solids. This is one of the reasons why the carbon chemistry is at the basis of the organic chemistry and the biochemistry from which life on earth was born. In this context, the surface chemistry assumes a substantial role dictating the physical and chemical properties of the carbon-based materials. Different functionalities are obtained by bonding carbon atoms with heteroatoms (mainly oxygen, nitrogen, sulfur) determining a certain reactivity of the compound which otherwise is rather weak. This holds for classic materials such as the diamond, the graphite, the carbon black and the porous carbon but functionalization is widely applied also to the carbon nanostructures which came at play mainly in the last two decades. As a matter of fact, nowadays, in addition to fabrication of nano and porous structures, the functionalization of CbMs is at the basis of a number of applications as catalysis, energy conversion, sensing, biomedicine, adsorption etc. This work is dedicated to the modification of the surface chemistry reviewing the different approaches also considering the different macro and nano allotropic forms of carbon.C 2019, 5, 84 3 of 45 narrow graphite-like interconnected layers. This leads to a closed pore rigid structure that is chemically inert, hard but brittle [48][49][50].Due to the highly resistant, conductive, and inert network, glassy carbons are utilized in a series of rather different applications. They are utilized as electrodes in solid state batteries and in industrial harsh chemical processes where also high temperatures are involved such as crystallization of CaF2, CdS and ZnS. Glassy carbon can be utilized to manufacture high temperature furnace elements. Due to the chemical inertness, glassy carbons are utilized also in fabrication of protheses. Porous carbon and carbon black are much softer. Generally, in industrial applications important is the extension of the surface which is exposed to the external environment. The porous carbon is characterized by a high specific surface area enhancing the interaction with the external medium. Although it possesses a lower conductivity with respect to glassy carbon, the high porosity and the presence of active sites makes it a good material to fabricate electrodes for applications in electrochemistry [51][52][53] and bioelectrodes for sensing and stimulation [54,55].The same holds for the carbon black mainly utilized as additive in rubbers and polymers to improve their mechanical properties, or as a pigment [56] although new potentialities have been recently envisaged [57].Common to all the forms of carbon which are bri...

show abstract

“…There is a global and ever-growing demand for wearable, foldable, and stretchable electronics in the energy, environmental monitoring and medical sectors to name but a few. [1][2][3] The chosen technology must provide spatially-defined control of the conductivity type and value, electrical contacts, and a dielectric material. Moreover, the materials have to be non-toxic, flexible, and stable at the pH of body sweat for wearable electronics.…”

Section: Introductionmentioning

confidence: 99%

Beyond graphene oxide: laser engineering functionalized graphene for flexible electronics

et al. 2020

View full text Add to dashboard Cite

show abstract

Graphene-Based Sensors for Human Health Monitoring

Cited by 238 publications

References 188 publications

Graphene-Oxide-Based Electrochemical Sensors for the Sensitive Detection of Pharmaceutical Drug Naproxen

Graphene-Oxide-Based Electrochemical Sensors for the Sensitive Detection of Pharmaceutical Drug Naproxen

The Role of Functionalization in the Applications of Carbon Materials: An Overview

Beyond graphene oxide: laser engineering functionalized graphene for flexible electronics

Contact Info

Product

Resources

About