Granulomatous ileocolitis

Crohn's disease of the colon.

“…Our clinical experience is similar in most respects to that reported by Lockhart-Mummery and Morson (1960Morson ( , 1964, Marshak et al (1966), and Jones, Lennard-Jones, and Lockhart-Mummery (1966). The age group involved is the same, with emphasis on the second and third decades, but we noted distinctly more females than males in contrast to the other series in which there was little difference between the sexes.…”

“…Toxic dilatation was documented in case 14. Janowitz and Present (1966) commented that toxic dilatation had yet to be described in this form of inflammatory disease of the large bowel, and Marshak et al (1966) concurred. Hawk and Turnbull (1966), however, stated that toxicdilatation of thecolon occurred as acomplication of regional enteritis in 14 of 87 patients (16%) with the same alarming suddenness as seen with ulcerative colitis, and Morson (1966) agreed that he had observed it.…”

“…The fact that Crohn's disease may involve the colon either initially or in association with small bowel disease is now firmly established due largely to the evidence presented by Lockhart-Mummery and Morson (1960Morson ( , 1964 and Marshak, Lindner, and Janowitz (1966). This entity is clearly distinct from ulcerative colitis and other forms of colonic disease.…”

Spread of lesions in Crohn's disease of the colon

“…Conservative treatment is widely recommended ( Van Patter, Bargen, Dockerty, Feldman, Mayo, and Waugh, 1954;Edwards, 1963;Lindner, Marshak, Wolf, and Janowitz, 1963;Laskin, 1964;Marshak, Lindner, and Janowitz, 1966;Crohn, 1967;Colcock and Braasch, 1968). Surgery is only considered to be indicated in cases refractory to medical treatment or when complications occur.…”

“…Further, the risk of spread of the lesions in Crohn's disease is generally considered insignificant, or even denied (Valdes-Dapena, 1964;Marshak et al, 1966).…”