Granuloma Faciale

Treatment of Granuloma Faciale With the 585-nm Pulsed Dye Laser

“…The sites of predilection are the sides (30%) and tip (7%) of the nose, preauricular area (22%), cheeks (22%), forehead (15%), tip of the nose (7%), and helix of the ear (4%). 4 Extrafacial granuloma faciale has also been reported but is rare. 5,6 The clinical differential diagnosis includes sarcoidosis, discoid lupus erythematosus, lymphocytic infiltrate of Jessner, polymorphous light eruption, rosacea, lymphoma cuffs, histiocytosis X, erythema elevatum diutinum, infectious granuloma, and basal cell carcinoma.…”

“…Medical modalities that have been proposed include colchicine, 12 dapsone, [13][14][15][16] 4,7,12 None of them have been consistently effective, and a large proportion of them have substantial wellknown adverse effects, such as hemorrhagic gastroenteritis, blood dyscrasias, oculotoxicity, nephrotoxicity, peripheral neuropathy, skin discoloration, actinic damage, atrophy, and adrenal suppression. 22 Surgical treatments have included wide excision, 2,20 cryotherapy, [23][24][25] radiation, 4,7,21 electrodesiccation with and without curettage, 4 and dermabrasion. 4,26 These modalities have been used with varying degrees of success, and all pose a significant risk for permanent pigmentary changes and scarring.…”

“…22 Surgical treatments have included wide excision, 2,20 cryotherapy, [23][24][25] radiation, 4,7,21 electrodesiccation with and without curettage, 4 and dermabrasion. 4,26 These modalities have been used with varying degrees of success, and all pose a significant risk for permanent pigmentary changes and scarring.…”

Granuloma eosinophilicum faciei - erfolgreiche kryochirurgische Behandlung bei sechs Patienten

“…Klinisch finden sich meist solitäre, nicht selten auch mehrere, asymptomatische, rötlich-bräunliche, flache bis knotige Plaques mit erweiterten Follikelostien. Sitz der Granulome ist nahezu immer das Gesicht, zumeist an Nase, Wange, Schläfe oder Stirn [2,9,15,25]. Multilokuläres Auftreten und extrafaciales Vorkommen ist beschrieben worden [10,14,15,18,21].…”

“…Langsame Grö-ßenzunahme und Schmerzlosigkeit sind für das Granuloma eosinophilicum faciei charakteristisch. Das Granuloma eosinophilicum faciei kann in jedem Lebensalter auftreten [2,9]. Betroffen sind jedoch meist Menschen mittleren Alters, vielen Angaben nach bevorzugt Männer [9,11,15].…”