Treatment of Granuloma Faciale With the 585-nm Pulsed Dye Laser

Complete Clearance of Resistant Granuloma Faciale With Pulsed Dye Laser After Pre-treatment With Mometasone and Tacrolimus

“…5 Several treatment options have been proposed for granuloma faciale; however, no modality has been shown to be consistently effective. 3 Some degree of success has been reported with topical or intralesional corticosteroids, however, they rarely yield satisfactory long-term results. 6 In addition, potential side effects particularly skin atrophy limit their prolonged use.…”

“…6 In addition, potential side effects particularly skin atrophy limit their prolonged use. 3 Topical tacrolimus as monotherapy may also be helpful. 7 It has been suggested that the accumulation of the inflammatory infiltrate in granuloma faciale is mediated by interferon-γ.…”

“…[8][9][10] There are isolated case reports on the use of systemic agents such as dapsone, colchicine, anti-malarials, isoniazid and clofazimine; however, they are neither consistently effective nor without risks of adverse effects. 2,3 Various lasers have been used to treat granuloma faciale, with variable efficacy. The carbon dioxide laser was one of the first lasers used.…”

“…The carbon dioxide laser was one of the first lasers used. 3 This laser causes non-selective vaporization of tissue with significant hypopigmentation and scarring. 3 The more recent use of a scanningassisted CO2 laser can however, reduce these adverse effects.…”

“…3 This laser causes non-selective vaporization of tissue with significant hypopigmentation and scarring. 3 The more recent use of a scanningassisted CO2 laser can however, reduce these adverse effects. 11 There are a few cases in which the argon laser was effective, 12 however, this benefit was limited by the development of collagenous scars.…”