Granulocytic sarcoma in the absence of myeloid leukemia

Nonmyeloablative allogeneic bone marrow transplantation for orbital granulocytic sarcoma associated with t(8;21)(q22;q22) in acute myeloid leukemia

“…From the experience of this patient and review of the literature, orbital masses as the initial presentation of AML should be considered in the differential diagnosis, even in the absence of typical leukemia symptoms. [1][2][3] Zimmerman et al 1 suggested that any orbital tumor looking like a malignant lymphoma should be expected to be a granulocytic sarcoma and that appropriate hematologic studies should be undertaken.…”

“…[1][2][3][4] Nonmyeloablative allogeneic stem cell transplantation has been reported by Slavin et al 5 to eradicate malignant host hematopoietic cells successfully. The aim of nonmyeloablative conditioning is to engraft donor immunohematopoietic cells to establish host-versus-graft tolerance for induction of graft-versus-malignant (GVM) effects to displace residual malignant host cells.…”

Myeloid Sarcoma as the Presenting Symptom of Chronic Myelogenous Leukemia Blast Crisis

“…P revious nomenclature for myeloid sarcoma included granulocytic sarcoma, myeloblastoma, extramedullary myeloid tumor, and chloroma. The term chloroma is derived from the Greek chloros, meaning green, as the tumor appears green when exposed to air (1). Myeloid sarcoma is associated with a small percentage of acute myelogenous leukemia (AML) cases, approximately 3% to 5% (2).…”

Cytodiagnosis of Granulocytic Sarcoma of Liver Arising in a Milieu of Myeloid Metaplasia

“…1 Granulocytic sarcoma can occur in any anatomic site and is known to involve the lymph nodes, bone, soft tissue, skin and breast. [2][3][4] It usually presents along with acute myelogenous leukemia, chronic myelogenous leukemia or other myeloproliferative disorders. [2][3][4][5] The morphologic recognition of this condition is challenging because of its diverse clinical presentations.…”