Grading follicular lymphoma on fine-needle aspiration specimens-A practical approach

Young, Nancy A.

doi:10.1002/cncr.21350

Cited by 38 publications

(43 citation statements)

References 31 publications

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“…The possibility to correlate proliferation with cell size and immunophenotype might allow for a better sub-classification of B-NHL by FC. Our findings need to be validated by others and might represent a useful method to distinguish by FC low-grade from high-grade lymphomas especially in small samples and fine needle aspirates (58).…”

Section: Discussionmentioning

confidence: 69%

Tissue flow cytometry immunophenotyping in the diagnosis and classification of non‐Hodgkin's lymphomas: A retrospective evaluation of 1,792 cases

Demurtas

Stacchini

Aliberti

et al. 2013

Cytometry Part B Clinical

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Section: Discussionmentioning

confidence: 69%

Tissue flow cytometry immunophenotyping in the diagnosis and classification of non‐Hodgkin's lymphomas: A retrospective evaluation of 1,792 cases

Demurtas

Stacchini

Aliberti

et al. 2013

Cytometry Part B Clinical

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“…The specific criteria and clinical significance of the grading will be discussed in a separate article. 55 Some T-cell-rich B-cell lymphomas at first glance appear to have a polymorphous population; however, upon closer evaluation they are composed of only two cell types, large B-cells and small T-cells. In other cases the small, mature lymphocytes may be dominant and obscure the large cells.…”

Section: Polymorphous Lymphoid Populationmentioning

confidence: 99%

Strategies to diagnose lymphoproliferative disorders by fine-needle aspiration by using ancillary studies

Caraway

2005

Cancer

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Graessley's theory has been applied to keratin/PEO concentrated aqueous solutions giving qualitative insight to the rheology of these polymer blends in electrospinning. The shear rate dependent viscosity of different blends was compared with that of pure polymer solutions. The characteristic time τη was calculated by the minimum value of $ \dot \gamma $ at the beginning of the non‐Newtonian viscosity behavior. Flow curves of PEO (at concentration from 1.0 to 7.0 wt %) reduce to a single curve by plotting η/η0 against $ \dot \gamma{\tau_\eta} $. Moreover, PEO solutions exhibit a linear proportionality between zero‐shear viscosity and the characteristic time η0 ∝ τη. Keratin/PEO blend solutions follow the same proportionality at very high and low keratin content, whereas linearity drops when the keratin content range from 50 to 70%. The departure from the theory has been interpreted as a sign of some interaction between the macromolecules of keratin and PEO. It was supposed that keratin displaces solvent molecules and expands the PEO chain coils increasing the relaxation time of the polymer solution. This behavior was correlated with changes in the morphology of the nanofibres produced by electrospinning from these polymer blends. Finally, additive rules to zero‐shear viscosity were applied to keratin and PEO solutions, indicating that the experimental η0 values were higher than the theoretical ones for all the proportions of the blends, especially for high keratin amount. © 2008 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 46: 1193–1201, 2008

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“…Although several studies have reported its feasibility [28], we did not grade FL on FNAB in our practice. However, we were able to grade FL, especially low-grade FL, on CNB.…”

Section: Discussionmentioning

confidence: 99%

Diagnosis of Lymphoma Using Fine-Needle Aspiration Biopsy and Core-Needle Biopsy: A Single-Institution Experience

Jelloul¹,

Navarro²,

Navale³

et al. 2019

Acta Cytologica

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Objective: The objective is to study the efficacy of fine-needle aspiration biopsy (FNAB) and core-needle biopsy (CNB) in the diagnosis of lymphoma in a single institution. Study Design: We retrospectively reviewed 635 FNAB/CNB cases performed in our institution to rule out lymphoma during a 4-year period and collected the relevant clinical and pathological information for statistical analysis. Results and Conclusions: This cohort comprised 275 males and 360 females, with a median age of 57 years. Among the 593 cases with adequate diagnostic materials for lymphoma work-up, 226 were positive for lymphoma, 286 were negative for lymphoma, and 81 were nondiagnostic. Each case had an FNAB, and 191 cases also underwent a CNB. The subclassification rate according to the WHO (2008) was 67% overall, 81% for the FNAB with CNB group, and 40% for the FNAB group. In the FNAB with CNB group, the subclassification rates for cases with and without a history of lymphoma were not significantly different. A definitive diagnosis of lymphoma relied on ancillary studies, but was not affected by location, or the needle gauge of CNB. Follow-up data revealed a high diagnostic accuracy of FNAB with CNB. In conclusion, the use of FNAB and CNB with ancillary studies is effective in providing a definitive diagnosis of lymphoma in our experience at the Northwell Health System.

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Grading follicular lymphoma on fine-needle aspiration specimens-A practical approach

Abstract: superb colleague, teacher, and hematopathologist, for his invaluable contributions to the field of cytopathology and hematopathology and expresses gratitude for his continued support of fine-needle aspiration in the diagnostic evaluation of non-Hodgkin lymphoma.

Cited by 38 publications

References 31 publications

Tissue flow cytometry immunophenotyping in the diagnosis and classification of non‐Hodgkin's lymphomas: A retrospective evaluation of 1,792 cases

Tissue flow cytometry immunophenotyping in the diagnosis and classification of non‐Hodgkin's lymphomas: A retrospective evaluation of 1,792 cases

Strategies to diagnose lymphoproliferative disorders by fine-needle aspiration by using ancillary studies

Diagnosis of Lymphoma Using Fine-Needle Aspiration Biopsy and Core-Needle Biopsy: A Single-Institution Experience

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