Goji (Lycium barbarumandL. chinense): Phytochemistry, Pharmacology and Safety in the Perspective of Traditional Uses and Recent Popularity

Abstract

Goji l " wolfberry l " Lycium barbarum l " Lycium chinense l " Solanaceae l " Novel Food

Bu-Shen-Ning-Xin decoction suppresses osteoclastogenesis <i>via </i>increasing dehydroepiandrosterone to prevent postmenopausal osteoporosis

“…Studies have focused on the antioxidant and immunomodulatory properties of this fruit in a range of age-related diseases such as atherosclerosis, neurodegeneration, and diabetes (61). The antioxidative action of this fruit is mainly attributed to polysaccharides and flavonoids (60). In Raw246.7 cells, polysaccharides induced expression of TNF-α and IL-1β via activation of NF-κB and AP-1 to modulate immunoreaction (35).…”

“…(To continue) (60), and neuroprotective action (57). Studies have focused on the antioxidant and immunomodulatory properties of this fruit in a range of age-related diseases such as atherosclerosis, neurodegeneration, and diabetes (61).…”

Chromatographic Determination of Phenolic Acids and Flavonoids in Lycium barbarum L. and Evaluation of Antioxidant Activity

“…The presence of various functional components like polysaccharides, flavonoids, and carotenoids in L. barbarum L. fruits is believed to be responsible for these effects (He et al 2012;Yao et al 2011). Several physiological studies have focused on polysaccharides and carotenoids; however, flavonoids have been less investigated, especially for their antioxidant activity (Amagase and Farnsworth 2011;Potterat 2010).…”

Effects of Lycium barbarum on bacterial translocation in thioacetamide-induced liver injury in rats

“…33 LBP may exert their beneficial effects in other ways, such as acting as bioactive fibers or prebiotics, by contributing to the synthesis and release of antioxidants by probiotic bacteria and inhibiting inflammation. 26,33,34 In this study, Lycium barbarum treatment evidently attenuated intestinal damage on the contrary liver damage. In the light of these data, our results suggest that interaction between Lycium barbarum and intestinal flora provides an important contribution to its antioxidant and anti-inflammatory effect in the intestine.…”

“…25 Lycium barbarum contains very important constituents such as carotenoids, polysaccharides, vitamins, and flavonoids. 26 In our study, Lycium barbarum powder was extracted with four solvents consecutively. There was no special reason for choosing these solvents and this method.…”