Goat pasteurellosis: serological analysis of circulating Pasteurella serotypes in Tanqua Aberegelle and Kola Tembien Districts, Northern Ethiopia

Assefa, Guash Abay; Kelkay, Mulalem Zenebe

doi:10.1186/s13104-018-3606-0

Cited by 13 publications

(14 citation statements)

References 8 publications

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“…In addition, co-infection with two or more serotypes on a single animal has been well recorded in almost all sampled (90.17%) animals. Similar findings have been reported by ( 11 , 45 ) in Northern Ethiopia. Whether multiple serotype infection exhibits a different clinical or immunological outcome as opposed to mono-serotype infections is an area of further investigation.…”

Section: Discussionsupporting

confidence: 92%

Serotyping and Seroprevalence of Mannheimia haemolytica, Pasteurella multocida, and Bibersteinia trehalosi and Assessment of Determinants of Ovine Pasteurellosis in West Amhara Sub-region, Ethiopia

et al. 2022

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A cross-sectional study was undertaken in four (4) districts of the West Amhara sub-region of Ethiopia with the aim of assessing the diversity and distribution of serotypes of Pasteurella species, their seroprevalence, and associated risk factors, and knowledge, attitude, and practice of farmers toward ovine pasteurellosis. A total of 600 sheep sera were collected using multistage cluster sampling. Each sample was examined for the presence of six (6) serotype-specific antibodies using an indirect haemagglutination test. We are reporting a higher seroprevalence of 90.17% (541/600) in which all seropositive animals were shown to have been co-infected with multiple serotypes. Individual serotype prevalence showed that serotype A7 has the highest prevalence of 77.83% followed by A2 (74.33%), T15 (64%), T4 (62%), PA (60%), and A1 (39.17%). In this study, being female [odds ratio (OR): 2.45, 95% CI (1.09–5.52), p = 0.031] and living in high altitude areas [OR: 20.29, 95% CI (2.54–161.95), p = 0.004] were found to be significantly associated with sero-positivity. A questionnaire survey (n = 384) employed in a face-to-face interview was used to assess the knowledge, attitude, and practice of farmers related to ovine pasteurellosis. Accordingly, the majority (72.4%) of respondents had an inadequate knowledge level of the disease. The proportion of farmers with a favorable attitude and good practices toward the disease was 50.26 and 77.6%, respectively. This study is highly indicative that ovine pasteurellosis is a ubiquitous disease in the study area challenging the sheep production sector. The existence of diverse serotypes reported to lack cross-protective immunity is likely to explain why the current vaccination practice with the mono-serotype Pasteurella multocida biotype A vaccine is not providing adequate protection against outbreaks of the disease. Prioritization of one or more serotypes for inclusion in a multivalent vaccine should be dictated by the abundance and distribution of a particular serotype, its clinical importance, and its resultant economic impact. Furthermore, training farmers on key aspects of the disease is vital in the implementation of effective disease management strategies through a participatory approach. Data from the remaining regions of the country could help realize the development of an effective vaccine that works best at the national level.

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Section: Discussionsupporting

confidence: 92%

Serotyping and Seroprevalence of Mannheimia haemolytica, Pasteurella multocida, and Bibersteinia trehalosi and Assessment of Determinants of Ovine Pasteurellosis in West Amhara Sub-region, Ethiopia

et al. 2022

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“…These results are nearly similar to that obtained by Momin et al (2011) who recovered P. multocida from black Bengal goats with a rate of 20% and Rashid et al (2013) who recovered P. multocida from goat lungs with a rate of 15% respectively. However, the overall prevalence of pasteurellosis in goats was 31.4% observed by Assefa et al (2018) contrasting our result.…”

Section: Resultscontrasting

confidence: 99%

Incidence and Antibiotic Susceptibility Profile of Pasteurella Maltocida Isolates Isolated from Goats in Savar Area of Bangladesh

Ahmed

Hasan

Islam

et al. 2019

ASD

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In Bangladesh, goat farming is substantially hampered due to outbreaks of respiratory infectious diseases like pneumonia causing morbidity, mortality and economic losses in Black Bengal goats. Among the infectious agents, Pasteurella maltocida is more frequently associated with the outbreak of acute pneumonia and death of goats. Hence, the occurrence of P. multocida in the goat population should be regularly investigated to effectively control the disease. Furthermore, antibiotic resistance/sensitivity profiling of P. maltocida also needs to be regularly updated for designing or updating of efficient treatment strategy. In this investigation, 150 nasal swab samples from goats were collected from Savar region of Bangladesh and on the basis of colony, staining and biochemical characteristics P. multocida were isolated in 25 samples. Disc diffusion assay was used to determine the antimicrobial susceptibility of 20 isolates against 9 different antimicrobial agents. This study revealed that the rate of P. multocida isolated from goats in Savar area was about 16.67%. The incidence of P. multocida was higher in goats affected with acute pneumonia than apparently healthy goats. P. multocida was fully resistant to penicillin and amoxicillin whereas showed high sensitivity towards ciprofloxacin followed by streptomycin and neomycin. This study suggests that ciprofloxacin, streptomycin and neomycin are potent anti-Pasteurella multocida drugs.

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“…Few previous studies attempted to identify the serotypes of bacteria involved in eld cases of pneumonic pasteurellosis of sheep and goats. For instance, in two districts of northern Ethiopia (Tanqua-Abergelle and Kola Tembien) 9 reported the predominance of P. multocida serotype A, M. haemolytica serotype A1, M. haemolytica serotype A2, and M. haemolytica serotype A7 in goats. Similar studies conducted by Berhe et al 10 showed the occurrence of these four serotypes in sheep and goats in Tanqua-Abergelle district.…”

Section: Respiratory Diseases Of Sheep and Goats Received Huge Veteri...mentioning

confidence: 99%

Identification of Serotypes of Mannheimia haemolytica and Pasteurella multocida from pneumonic cases of sheep and goats and their antimicrobial sensitivity profiles in Borana and Arsi zones, Ethiopia

Girma

Getachew

Beyene

et al. 2022

Preprint

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Respiratory diseases caused by M. haemolytica and P. multocida have been known to result in a considerable loss due to mortality and reduced production. This study aimed at isolation and identification of M. haemolytica and P. multocida associated with pneumonic pasteurellosis in sheep and goats using bacteriological and molecular techniques. Identification of serotypes of M. haemolytica and P. multocida was done using indirect haemagglutination test (IHAT). The in vitro antimicrobial sensitivity profiles of the M. haemolytica were tested using standard disk diffusion method. A total of 52 and 78 nasal swabs were collected from pneumonic cases for bacterial isolation and identification in Borana and Arsi zone, respectively. Four hundred sera samples were collected for identification of serotypes. The results showed that 17 of 52 (32.69%; 95% CI: 20.33, 47.11) nasal swabs collected from pneumonic animals in Borana yielded positive results for Pasteurella / Mannheimia species, 13 (25.00%; 95% CI: 14.03, 38.95) of which were M. haemolytica. None of the samples yielded P. multocida. Twenty-three of 78 (29.49%; 95% CI: 19.69, 40.89) nasal swabs collected from pneumonic animals yielded positive results for M. haemolytica (17) and P. multocida (6). Secondary biochemical characterization revealed that 14 of the 17 isolates conform to M. haemolytica whereas none of the 6 isolates suspected to be P. mutocida were confirmed. Eleven (84.62%) isolates from Borana and 4 (28.57%) from Arsi were confirmed to be M. haemolytica using PCR targeting the Rpt2 genes. None of the isolates with cultural and morphological features of P. multocida gave positive results by molecular assay. Serological assay identified three serotypes of M. haemolytica namely A1, A2 and A7 almost in all of the samples whereas P. multocida serotype A was detected in 78.75% of the samples. The M. haemolytica isolates tested for susceptibility to antibiotics showed resistance against Bacitracin (83.33%) and Penicillin (50.00%) while were found susceptible to Gentamycin, Chloramphenicol and Sulfamethoxazole (100%) and Tetracycline (83.33%). In conclusion, the results of the present study revealed the association of M. haemolytica with pneumonic pasteurellosis in sheep and goats and can be of use in vaccine development in Ethiopia. Nevertheless, further investigations and continuous monitoring of antimicrobial resistance and appropriate selection and prudent use of antimicrobials in livestock sector are required.

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Goat pasteurellosis: serological analysis of circulating Pasteurella serotypes in Tanqua Aberegelle and Kola Tembien Districts, Northern Ethiopia

Cited by 13 publications

References 8 publications

Serotyping and Seroprevalence of Mannheimia haemolytica, Pasteurella multocida, and Bibersteinia trehalosi and Assessment of Determinants of Ovine Pasteurellosis in West Amhara Sub-region, Ethiopia

Serotyping and Seroprevalence of Mannheimia haemolytica, Pasteurella multocida, and Bibersteinia trehalosi and Assessment of Determinants of Ovine Pasteurellosis in West Amhara Sub-region, Ethiopia

Incidence and Antibiotic Susceptibility Profile of Pasteurella Maltocida Isolates Isolated from Goats in Savar Area of Bangladesh

Identification of Serotypes of Mannheimia haemolytica and Pasteurella multocida from pneumonic cases of sheep and goats and their antimicrobial sensitivity profiles in Borana and Arsi zones, Ethiopia

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