Incidence and Antibiotic Susceptibility Profile of Pasteurella Maltocida Isolates Isolated from Goats in Savar Area of Bangladesh

Abstract

In Bangladesh, goat farming is substantially hampered due to outbreaks of respiratory infectious diseases like pneumonia causing morbidity, mortality and economic losses in Black Bengal goats. Among the infectious agents, Pasteurella maltocida is more frequently associated with the outbreak of acute pneumonia and death of goats. Hence, the occurrence of P. multocida in the goat population should be regularly investigated to effectively control the disease. Furthermore, antibiotic resistance/sensitivity profiling of P. maltocida also needs to be regularly updated for designing or updating of efficient treatment strategy. In this investigation, 150 nasal swab samples from goats were collected from Savar region of Bangladesh and on the basis of colony, staining and biochemical characteristics P. multocida were isolated in 25 samples. Disc diffusion assay was used to determine the antimicrobial susceptibility of 20 isolates against 9 different antimicrobial agents. This study revealed that the rate of P. multocida isolated from goats in Savar area was about 16.67%. The incidence of P. multocida was higher in goats affected with acute pneumonia than apparently healthy goats. P. multocida was fully resistant to penicillin and amoxicillin whereas showed high sensitivity towards ciprofloxacin followed by streptomycin and neomycin. This study suggests that ciprofloxacin, streptomycin and neomycin are potent anti-Pasteurella multocida drugs.

Multi-drug Resistant Mannheimia hemolytica and Pasteurella multocida in Pneumonic Sheep in Bangladesh

“…The choice of antimicrobials is crucial due to the increased wide spread antimicrobial resistance narrowing down the effective antimicrobial spectrum. Despite not as highlighted as other bacteria, Mannheimia hemolytica and PM isolated from sheep and goat are gaining attention due to their rising antimicrobial resistance behavior in recent years 26 . In this study, Chloramphenicol was the only drug that was 100% sensitive to the both isolates followed by Sulfonamide 78.22, 63.33 to Pasteurella multocida and Mannheimia hemolytica respectively.…”