GMOs in Russia: Research, Society and Legislation

Коробко, И. В.; Georgiev, Pavel; Skryabin, K. G.; Kirpichnikov, Mikhaǐl P.

doi:10.32607/20758251-2016-8-4-6-13

Cited by 8 publications

(4 citation statements)

References 23 publications

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“…In recent decades, although in most countries the use of genetically modified organisms (GMOs) was prohibited or heavily regulated, it has been proposed to change the present regulations [ 20 , 21 ]. In fact, the amount of commercially available GMOs has been continuously rising in recent years [ 22 ].…”

Section: Discussionmentioning

confidence: 99%

An engineered food-grade Lactococcus lactis strain for production and delivery of heat-labile enterotoxin B subunit to mucosal sites

et al. 2017

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BackgroundRecent researches have been focusing on mucosal immune adjuvants, which play the key roles in mucosal immunization and have become the limitation for non-injected vaccine development. Escherichia coli heat-labile enterotoxin B subunit (LTB) was regarded as a promising mucosal adjuvant for its nontoxicity and potent activity. LTB preparation issues have always been recurring, in part owing to that the recombinant LTB expressed by E. coli does not act as its native form.ResultsWe constructed an engineered Lactococcus lactis strain using a food-grade expression system. The LTB secreted by the engineered strain was detected in the culture supernatant, constituting 10.3% of the supernatant proteins, and recognized by mouse anti-LTB antibodies. The engineered strain, co-administered orally to SPF BALB/c mice with a H. pylori vaccine candidate expressing Lpp20 antigen, could significantly enhance the Lpp20-induced mucosal SIgA antibody responses against H. pylori.ConclusionsThis is the first report that LTB was efficiently produced and delivered via using a food-grade lactococcal expression system, which offers a novel production and utilization mode of this crucial mucosal adjuvant. The engineered L. lactis strain secreting LTB has considerable potential for oral vaccine formulation owing to its outstanding safety, adjuvant activity and high-level production.Electronic supplementary materialThe online version of this article (doi:10.1186/s12896-017-0345-6) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 99%

An engineered food-grade Lactococcus lactis strain for production and delivery of heat-labile enterotoxin B subunit to mucosal sites

et al. 2017

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“…Since potato has excellent availability of genomic resources as well as genome sequence and efficient transformation systems, several workers used various genome editing approaches viz. zinc-finger nucleases (ZFNs) [133][134][135][136][137] for improving traits like herbicide resistance, modification of starch, bio-fortification and reducing anti-nutritional factors to enhance overall increased quality of produce. Earlier for targeting traits like insect resistance, proteins, vitamins and carotenoids, transgenic technology was extensively used.…”

Section: Breeding Behavior Of Potato: From Conventional To New Breeding Technologiesmentioning

confidence: 99%

Visiting Potato from a Breeding Perspective: Accomplishments and Prospects

Brar¹,

Sharma²,

Kaushik³

2021

Solanum Tuberosum - A Promising Crop for Starvation Problem

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Several enhancements to the conventional potato breeding are possible though they have encouragement as well as limitations. I n this direction, the marker-assisted selection may be utilized to stack major genes as well as QTLs. Whereas the genetic transformation and genome editing methods accelerate the process of ricking of genes/transgenes. Moreover, these methodologies supplemented with the next-generation sequencing (NGS) platforms and pipelines further aid in reaching the potato ideotype. Here, we overviewed the critical topics that are related to potatoes, from general background, breeding behavior, breeding approaches employed to the potato improvement. Overall, this information complied might serve as background information that is important for potato breeders.

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“…Whether some of these GMOs and products can be re-exported to EU, and whether they would be labelled as GMOs is not clear. Moreover, in addition to GMO varieties commercialized by predominantly US companies, Russian scientists have developed a number of domestic GM plant varieties, e.g., Bt toxin-producing insect resistant potato varieties (see the RF patents listed by Korobko et al., 2016) and herbicide tolerant wheat varieties (Miroshnichenko et al., 2007). Transgenic virus resistant sugar beet, as well as GM potatoes resistant to viral and fungal pathogens have also been reported (Skryabin, 2010).…”

Section: Main Textmentioning

confidence: 99%

Genetically modified seeds and plant propagating material in Europe: potential routes of entrance and current status

Rostoks

Grantina-Ievina

Ievina³

et al. 2019

Heliyon

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Genetically modified organisms (GMO), mainly crop plants, are increasingly grown worldwide leading to large trade volumes of living seeds and other plant material both for cultivation and for food and animal feed. Even though all the traded GMOs have been assessed for their safety with regards to human and animal health and the environment, there still are some concerns regarding the potential uncontrolled release in the environment of authorized or unauthorized GM plants. In this review, we identify the possible entrance routes of GM seeds and other propagating plant material in the EU which could be linked to unauthorized release of GMOs in the environment. In addition, we discuss the situation with GM plant cultivation in some non-EU countries in terms of potential risks for GM seed imports. The available body of information suggests that GM seeds and plant propagating material can enter the EU due to problems with labeling/traceability of GM seed lots, contamination of conventional seed lots and accidental release into the environment of grains imported for food and animal feed. Even though cases of uncontrolled release of authorized GMOs, as well as, release of unauthorized GMOs have been reported, they can be generally attributed to adventitious and technically unavoidable presence with little environmental impact. In conclusion, the probability of GM seeds and plant propagating material illegally entering the cultivation in EU is unlikely. However, specific monitoring programs need to be established and maintained to facilitate the compliance of European farmers with the current GMO legislation.

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GMOs in Russia: Research, Society and Legislation

Cited by 8 publications

References 23 publications

An engineered food-grade Lactococcus lactis strain for production and delivery of heat-labile enterotoxin B subunit to mucosal sites

An engineered food-grade Lactococcus lactis strain for production and delivery of heat-labile enterotoxin B subunit to mucosal sites

Visiting Potato from a Breeding Perspective: Accomplishments and Prospects

Genetically modified seeds and plant propagating material in Europe: potential routes of entrance and current status

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