Glucose tolerance status in 510 children and adolescents attending an obesity clinic in Central Italy

Abstract

Glucose metabolism alterations are frequently found among children and adolescents with overweight/obesity from Central Italy. Age, fasting glucose, and insulin resistance are main predictors of IGT. We suggest the use of OGTT as a screening tool in obese European adolescents.

Hepatic Steatosis among Obese Children and Adolescents

“…17 In our study, prevalence of IGT was 12% which was consistent with 17.1% and 11.2% in different studies done in Bangladesh 17 and abroad. 18 The prevalence of diabetes mellitus was 6%, this figure was also consistent with other studies where it was 4%. 19 In present study, the prevalence of high SGPT among obese children was 36%.…”

Elevated glucose level at 30 minutes during an oral glucose tolerance test in obese adolescents: a new disorder of glucose tolerance

“…BMI, IL-6, neopterin, fibrinogen, CRP, and Lp-PLA 2 lar diseases [27,28]. In this study, we demonstrated marked increases of IL-6, neopterin and Lp-PLA 2 in obese adolescents with elevated glucose level at 30 min compared to NGT and IGT groups.…”

“…Obesity is associated with alterations in glucose metabolism that may be present in adolescents. OGTT is a screening tool necessary to assess the risk of alterations in glucose metabolism in obese adolescents [27,28]. In our clinic, all adolescents with obesity, defined as having a BMI equal to or greater than the age-and sexspecific cutpoints, undergo 2-h OGTT.…”

Perbandingan Kadar Gula Darah Puasa pada Anak Obes dengan Resistensi Insulin dan Tanpa Resistensi Insulin

“…Namun, apakah obesitas terjadi pada awal atau setelah hiperinsulinemia masih belum diketahui pasti. Secara konseptual, mekanisme yang diusulkan untuk menjelaskan kausalitas adalah mekanisme penumpuk- 16 di sebuah klinik obesitas di Italia, juga ditemukan bahwa obesitas lebih banyak pada anak laki-laki (56,7%) daripada anak perempuan (43,3%). Pada penelitian kami, anak obes yang mengalami resistensi insulin didapatkan 34 (63%) sampel, di antaranya 23 (67,6%) berjenis kelamin laki-laki, dan 11 (32,4%) anak perempuan.…”