Hepatic Steatosis among Obese Children and Adolescents

Shelim, Rumana; Mohsin, Fauzia; Begum, Tahmina; Ma, Bin; Mahbuba, Sharmin; Islam, Rubaiya

doi:10.3329/jbcps.v34i2.32290

Cited by 2 publications

(4 citation statements)

References 13 publications

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“…This corresponds with other studies conducted in Bangladesh, China and Iran which showed that NAFLD among children were mostly mild. 12,16,17 A comparison of age and anthropometric measurements between children with NAFLD and non-NAFLD in our study showed statistical similarly. In contrast, Rong et al found that BMI in NAFLD group was significantly higher than non-NAFLD group, and Rafeey et al and Chan et al showed in their studies, that NAFLD was positively correlated with BMI and waist circumference.…”

Section: Discussionsupporting

confidence: 65%

“…This is supported by result of Shelim et al who found high ALT in NAFLD group than non-NAFLD group (p=0.04). 12 A raised ALT level was also noted among 47.1 and 30% children with NAFLD in studies by Rafeey et al and Pawer et al respectively. 15,17 These indicates a raised ALT among otherwise apparently healthy overweight and obese children should raise concern about presence of NAFLD among them.…”

Section: Discussionmentioning

confidence: 75%

“…This is concordant with a previous study which found NAFLD in 36% of obese Bangladeshi children. 12 While Chinese obese children were found to have hepatic steatosis in 77% cases by Chan et al and in 68.18% cases by Fu et al 13,14 In India a study by Pawar et al found that prevalence of nonalcoholic fatty liver disease in obese and overweight children was 62%. 15 NAFLD is classified as mild, moderate, and severe.…”

Section: Discussionmentioning

confidence: 98%

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Non-alcoholic fatty liver disease in obese and overweight children

Akhter¹,

Begum

Alam

et al. 2021

Int J Contemp Pediatr

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Background: Childhood obesity is rising alarmingly and approaching an epidemic proportion in many countries. It increases the risk of developing non-communicable disease in adulthood. Non-alcoholic fatty liver disease (NAFLD) is a key co-morbidity associated with obesity and emerged as the leading cause of chronic liver disease in children. This study aimed to see the prevalence of the NAFLD with overweight and obesity among children.Methods: It was a cross sectional study conducted among children aged 5.5 to 18 years attending in the pediatric endocrinology clinic of department of pediatrics, Bangabandhu Sheikh Mujib medical university over a period of 14 months. Children’s weight and height were evaluated and then BMI was calculated for particular age and sex according to center for disease control growth chart. All obese and overweight children were included except those taking systemic steroid, or suffering from genetic, endocrine, liver or renal disease. Patients were advised to do serum alanine aminotransferase (ALT) and ultrasonography of hepatobiliary system.Results: A total of 90 children were enrolled in the study. Among them majority (93.3%) were obese and the rest were overweight (6.7%). Overall, 40% children had NAFLD including 40.5% among the obese and 33.3% among the overweight (p>0.05). Majority (91.6%) had mild NAFLD. Alanine amino transferase (ALT) level was raised significantly among children with NAFLD compared to those without NAFLD (58.3% and 16.7% respectively, p<0.001).Conclusions: More than one-third of the overweight and obese children had NAFLD with a significantly higher level of ALT compared to children without NAFLD. Therefore, NAFLD should be routinely screened among children with increased weight to take timely intervention and prevent further progression of the disease.

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Section: Discussionsupporting

confidence: 65%

Section: Discussionmentioning

confidence: 75%

Section: Discussionmentioning

confidence: 98%

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Non-alcoholic fatty liver disease in obese and overweight children

Akhter¹,

Begum

Alam

et al. 2021

Int J Contemp Pediatr

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“…For example hepatomegaly is a frequent clinical finding in children that may be caused by intrinsic liver diseases or by other diseases with liver involvement . With the growing epidemic of childhood obesity, early detection of hepatic steatosis is critical to avoiding premature liver failure . In children with kidney disease, the renal size may be increased or decreased .…”

mentioning

confidence: 99%

Liver, Spleen, and Kidney Size in Children as Measured by Ultrasound: A Systematic Review

Calle‐Toro

Back

Viteri

et al. 2019

J of Ultrasound Medicine

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Ultrasound is commonly the first‐line imaging modality for assessing the pediatric abdomen. An abnormal size of the liver, spleen, or kidneys may indicate disease, but the evaluation is challenging because the normal size changes with age. In addition, published normal value charts for children may vary by population and methods. In this systematic review, we summarized published data on the normal size of the pediatric liver, spleen, and kidneys as measured by ultrasound in which we found similar values across different populations, ages, and sexes.

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Hepatic Steatosis among Obese Children and Adolescents

Cited by 2 publications

References 13 publications

Non-alcoholic fatty liver disease in obese and overweight children

Non-alcoholic fatty liver disease in obese and overweight children

Liver, Spleen, and Kidney Size in Children as Measured by Ultrasound: A Systematic Review

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