Glucans of Pleurotus florida blue variant: Isolation, purification, characterization and immunological studies

Dey, Biswajit; Bhunia, Sanjoy K.; Maity, Kankan K.; Patra, Sukesh; Mandal, Soumitra; Maiti, Swatilekha; Maiti, Tapas K.; Sikdar, Samir R.; Islam, Syed S.

doi:10.1016/j.ijbiomac.2012.01.031

Cited by 25 publications

(9 citation statements)

References 42 publications

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“…In addition, a number of studies demonstrated that this polysaccharide had many medicinal effects in human organisms including immune modulation and antibacterial activity [4,5,6]. Many other species of genus Pleurotus have been used for the isolation and characterization of bioactive glucans, for example P. eryngii [7,8], P. florida [9,10], P. ostreatoroseus [7,11], P. pulmonarius [12,13], P. tuber-regium [14] and P. sajor-caju [15,16,17]. Besides various glucans, water-soluble branched 3- O -methylated mannogalactans were also isolated from these mushrooms [18,19].…”

Section: Introductionmentioning

confidence: 99%

Polysaccharides from Basidiocarps of Cultivating Mushroom Pleurotus ostreatus: Isolation and Structural Characterization

et al. 2019

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Oyster mushrooms are an interesting source of biologically active glucans and other polysaccharides. This work is devoted to the isolation and structural characterization of polysaccharides from basidiocarps of the cultivated oyster mushroom, Pleurotus ostreatus. Five polysaccharidic fractions were obtained by subsequent extraction with cold water, hot water and two subsequent extractions with 1 m sodium hydroxide. Branched partially methoxylated mannogalactan and slightly branched (1→6)-β-d-glucan predominated in cold- and hot-water-soluble fractions, respectively. Alternatively, these polysaccharides were obtained by only hot water extraction and subsequent two-stage chromatographic separation. The alkali-soluble parts originating from the first alkali extraction were then fractionated by dissolution in dimethyl sulfoxide (DMSO). The polysaccharide insoluble in DMSO was identified as linear (1→3)-α-d-glucan, while branched (1→3)(1→6)-β-d-glucans were found to be soluble in DMSO. The second alkaline extract contained the mentioned branched β-d-glucan together with some proteins. Finally, the alkali insoluble part was a cell wall complex of chitin and β-d-glucans.

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Section: Introductionmentioning

confidence: 99%

Polysaccharides from Basidiocarps of Cultivating Mushroom Pleurotus ostreatus: Isolation and Structural Characterization

et al. 2019

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“…In China, P. abalonus (also known as Baoyugu) are traditional medicinal or edible fungus, and it is also a popular nutritional supplement which can reduce cancer risk [10]. Indeed, several recent studies have indicated that the polysaccharides from the mycelia and fruit bodies of different genus Pleurotus, Pleurotus sajor-caju, P. ostreatus, Pleurotus citrinopileatus, and Pleurotus florida can inhibit the growth of several types of cancers [11][12][13][14][15]. In this regard, the polysaccharides extracted from P. abalonus may play a promising role in the prevention of cancers.…”

Section: Introductionmentioning

confidence: 99%

Antioxidant and antitumor effects of polysaccharides from the fungus Pleurotus abalonus

Ren

Jiao

Yang

et al. 2015

Chemico-Biological Interactions

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“…'Florida' (syn. Pleurotus florida) α-1,6-glucan and α-1, 3-, β-1,6-d-glucan Stimulates macrophages, splenocytes and thymocytes [45,46] Pleurotus ostreatus Pleuran, heterogalactan, proteoglycan Induces IL-4 and IFN-γ production [47] Poria cocos…”

Section: Source Active Compound Immunomodulatory Effect Refsmentioning

confidence: 99%

Immunomodulatory Effects of Edible and Medicinal Mushrooms and Their Bioactive Immunoregulatory Products

Zhao

Gao

Rong

et al. 2020

JoF

102

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Mushrooms have been valued as food and health supplements by humans for centuries. They are rich in dietary fiber, essential amino acids, minerals, and many bioactive compounds, especially those related to human immune system functions. Mushrooms contain diverse immunoregulatory compounds such as terpenes and terpenoids, lectins, fungal immunomodulatory proteins (FIPs) and polysaccharides. The distributions of these compounds differ among mushroom species and their potent immune modulation activities vary depending on their core structures and fraction composition chemical modifications. Here we review the current status of clinical studies on immunomodulatory activities of mushrooms and mushroom products. The potential mechanisms for their activities both in vitro and in vivo were summarized. We describe the approaches that have been used in the development and application of bioactive compounds extracted from mushrooms. These developments have led to the commercialization of a large number of mushroom products. Finally, we discuss the problems in pharmacological applications of mushrooms and mushroom products and highlight a few areas that should be improved before immunomodulatory compounds from mushrooms can be widely used as therapeutic agents.

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Glucans of Pleurotus florida blue variant: Isolation, purification, characterization and immunological studies

Cited by 25 publications

References 42 publications

Polysaccharides from Basidiocarps of Cultivating Mushroom Pleurotus ostreatus: Isolation and Structural Characterization

Polysaccharides from Basidiocarps of Cultivating Mushroom Pleurotus ostreatus: Isolation and Structural Characterization

Antioxidant and antitumor effects of polysaccharides from the fungus Pleurotus abalonus

Immunomodulatory Effects of Edible and Medicinal Mushrooms and Their Bioactive Immunoregulatory Products

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