Globalization and Chagas Disease

Dias, João Carlos Pinto; Coura, José Rodrigues

doi:10.5772/38861

Cited by 2 publications

(1 citation statement)

References 26 publications

(30 reference statements)

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“…Untreated patients suffering acute Chagas infection can develop cardiac, digestive, or neurologic complications. [60,61] Diagnosis of infection by T. cruzi is based on epidemiology and clinics but must have its etiology confirmed by laboratory diagnosis. The latter may be performed through direct visualization of the parasite or through the immunological response of the infected host.…”

Section: Diseases Caused By Protozoamentioning

confidence: 99%

Electrochemical Biosensing for the Diagnosis of Viral Infections and Tropical Diseases

2017

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Rapid and reliable diagnosis of viral infections and tropical diseases and timely initiation of appropriate treatment are essential for their successful clinical management. This Review summarizes some basic concepts regarding the main viral infection and tropical diseases to which society is facing today and the conventional methods available for their detection. The tremendous potential offered by electrochemical affinity biosensors to address this important challenge, meeting the required demands for viral infections and tropical diseases diagnosis, is clearly stated by discussing challenges, opportunities, implementation, and application of selected examples focused on the determination of specific biomarkers of different molecular (genetic, regulatory, and functional) levels. The highlighted approaches demonstrate the use of a plethora of specific receptors and assay formats and a great diversity of attractive electrochemical approaches in this rapidly advancing and highly interesting field.

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Section: Diseases Caused By Protozoamentioning

confidence: 99%